Matches in SemOpenAlex for { <https://semopenalex.org/work/W2323861490> ?p ?o ?g. }
- W2323861490 endingPage "89" @default.
- W2323861490 startingPage "82" @default.
- W2323861490 abstract "Giant-cell tumor of bone (GCTB) is a locally aggressive histologically benign neoplasm with a less common malignant counterpart. Longitudinal data sources on GCTB are sparse, limited to single institution case series or surgical outcomes studies. The Swedish Cancer Registry is one of the few national population-based databases recording GCTB, representing a unique source to study GCTB epidemiology. We estimated incidence rate (IR) and overall mortality rates based on registry data. We identified patients with a GCTB diagnosis in the Swedish Cancer Registry from 1983 to 2011: benign (ICD-7 196.0–196.9; PAD 741) and malignant (PAD 746). Results were stratified by age at diagnosis, gender, and anatomical lesion location. The cohort included 337 GCTB cases (IR of 1.3 per million persons per year). The majority (n = 310) had primary benign GCTB (IR of 1.2 per million per year). Median age at diagnosis was 34 years (range 10–88) with 54% (n = 183) females. Malignant to benign ratio for women was 0.095 (16/167) and for men 0.077 (11/143). Incidence was highest in the 20–39 years age group (IR of 2.1 per million per year). The most common lesion sites were distal femur and proximal tibia. Mortality at 20 years from diagnosis was 14% (n = 48) and was slightly higher for axial (17%; n = 6) and pelvic (17%; n = 4) lesions. Recurrence occurred in 39% of primary benign cases and 75% of primary malignant cases. In our modern population-based series primary malignant cases were uncommon (8%), peak incidence 20–39 years with slight predominance in women. Recurrence rates remain significant with overall 39% occurring in benign GCTB, and 75% in malignant form. The linkage between databases allowed the first population based estimates of the proportion of patients who received surgery at initial GCTB diagnosis, and those who also received subsequent surgeries." @default.
- W2323861490 created "2016-06-24" @default.
- W2323861490 creator A5010584152 @default.
- W2323861490 creator A5016239771 @default.
- W2323861490 creator A5021543049 @default.
- W2323861490 creator A5033988683 @default.
- W2323861490 creator A5034572004 @default.
- W2323861490 creator A5042122044 @default.
- W2323861490 creator A5062908889 @default.
- W2323861490 creator A5067531937 @default.
- W2323861490 date "2016-06-01" @default.
- W2323861490 modified "2023-10-01" @default.
- W2323861490 title "Population-based study of giant cell tumor of bone in Sweden (1983–2011)" @default.
- W2323861490 cites W1507649428 @default.
- W2323861490 cites W1559130591 @default.
- W2323861490 cites W1714306007 @default.
- W2323861490 cites W1939135436 @default.
- W2323861490 cites W1964791284 @default.
- W2323861490 cites W1965247641 @default.
- W2323861490 cites W1982553403 @default.
- W2323861490 cites W1987418771 @default.
- W2323861490 cites W2016987712 @default.
- W2323861490 cites W2045837158 @default.
- W2323861490 cites W2051456934 @default.
- W2323861490 cites W2056155872 @default.
- W2323861490 cites W2072706774 @default.
- W2323861490 cites W2074946154 @default.
- W2323861490 cites W2075593962 @default.
- W2323861490 cites W2080074604 @default.
- W2323861490 cites W2081674519 @default.
- W2323861490 cites W2087282829 @default.
- W2323861490 cites W2089038909 @default.
- W2323861490 cites W2090082358 @default.
- W2323861490 cites W2100757960 @default.
- W2323861490 cites W2101687609 @default.
- W2323861490 cites W2109036427 @default.
- W2323861490 cites W2131756199 @default.
- W2323861490 cites W2147017066 @default.
- W2323861490 cites W2149821313 @default.
- W2323861490 cites W2153370061 @default.
- W2323861490 cites W2155769183 @default.
- W2323861490 cites W2158648264 @default.
- W2323861490 cites W2159152276 @default.
- W2323861490 cites W2167428574 @default.
- W2323861490 cites W2170527535 @default.
- W2323861490 cites W2288233972 @default.
- W2323861490 cites W4230172211 @default.
- W2323861490 cites W4292542148 @default.
- W2323861490 cites W4294856490 @default.
- W2323861490 cites W4294956794 @default.
- W2323861490 cites W4322695778 @default.
- W2323861490 doi "https://doi.org/10.1016/j.canep.2016.03.014" @default.
- W2323861490 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27060625" @default.
- W2323861490 hasPublicationYear "2016" @default.
- W2323861490 type Work @default.
- W2323861490 sameAs 2323861490 @default.
- W2323861490 citedByCount "34" @default.
- W2323861490 countsByYear W23238614902017 @default.
- W2323861490 countsByYear W23238614902018 @default.
- W2323861490 countsByYear W23238614902019 @default.
- W2323861490 countsByYear W23238614902020 @default.
- W2323861490 countsByYear W23238614902021 @default.
- W2323861490 countsByYear W23238614902022 @default.
- W2323861490 countsByYear W23238614902023 @default.
- W2323861490 crossrefType "journal-article" @default.
- W2323861490 hasAuthorship W2323861490A5010584152 @default.
- W2323861490 hasAuthorship W2323861490A5016239771 @default.
- W2323861490 hasAuthorship W2323861490A5021543049 @default.
- W2323861490 hasAuthorship W2323861490A5033988683 @default.
- W2323861490 hasAuthorship W2323861490A5034572004 @default.
- W2323861490 hasAuthorship W2323861490A5042122044 @default.
- W2323861490 hasAuthorship W2323861490A5062908889 @default.
- W2323861490 hasAuthorship W2323861490A5067531937 @default.
- W2323861490 hasConcept C107130276 @default.
- W2323861490 hasConcept C120665830 @default.
- W2323861490 hasConcept C121332964 @default.
- W2323861490 hasConcept C141071460 @default.
- W2323861490 hasConcept C142724271 @default.
- W2323861490 hasConcept C187212893 @default.
- W2323861490 hasConcept C2777190185 @default.
- W2323861490 hasConcept C2778527826 @default.
- W2323861490 hasConcept C2908647359 @default.
- W2323861490 hasConcept C61511704 @default.
- W2323861490 hasConcept C71924100 @default.
- W2323861490 hasConcept C72563966 @default.
- W2323861490 hasConcept C77076574 @default.
- W2323861490 hasConcept C99454951 @default.
- W2323861490 hasConceptScore W2323861490C107130276 @default.
- W2323861490 hasConceptScore W2323861490C120665830 @default.
- W2323861490 hasConceptScore W2323861490C121332964 @default.
- W2323861490 hasConceptScore W2323861490C141071460 @default.
- W2323861490 hasConceptScore W2323861490C142724271 @default.
- W2323861490 hasConceptScore W2323861490C187212893 @default.
- W2323861490 hasConceptScore W2323861490C2777190185 @default.
- W2323861490 hasConceptScore W2323861490C2778527826 @default.
- W2323861490 hasConceptScore W2323861490C2908647359 @default.
- W2323861490 hasConceptScore W2323861490C61511704 @default.
- W2323861490 hasConceptScore W2323861490C71924100 @default.