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- W2323916074 abstract "Prion diseases (transmissible encephalopathies) are progressive neurodegenerative diseases of animals and humans caused by a unique agent, the prion. These diseases have recently been in the news because of the emergence of bovine spongiform encephalopathy (BSE; mad cow disease) and variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom. Prion diseases may be sporadic, genetic, or acquired. Transmission results from abnormally folded proteins rather than nucleic acids. This article briefly reviews the molecular biology and biochemistry of the prion agent, the prion diseases, the evidence linking BSE to vCJD disease, and protocols for the handling and decontamination of prion-infected materials." @default.
- W2323916074 created "2016-06-24" @default.
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- W2323916074 date "1999-05-01" @default.
- W2323916074 modified "2023-09-23" @default.
- W2323916074 title "Prions and Prion Diseases" @default.
- W2323916074 doi "https://doi.org/10.1093/labmed/30.5.335" @default.
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