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- W2323978384 abstract "At Royal Prince Alfred Hospital, during the past 18 yr, 56 patients with diffuse lung disease were subjected to thoracotomy to obtain a lung biopsy. Most specimens were taken from the sharp margin of the lung and only a few from the lateral surface. In 9 patients the appearances were suggestive of allergic alveolitis. One of these had farmer's lung and 3 had been exposed to birds. Six specimens showed desquamative interstitial pneumonia, 2 with severe honeycombing, 2 with early honeycombing and 2 without fibrosis. In one of the latter, the changes were mild and there were also some intranuclear inclusions. Two patients had asbestosis and in both, the histological appearances otherwise resembled desquamative interstitial pneumonia. There were 4 biopsies from patients with eosinophilic granuloma, 3 in the active phase and one healing. Non-specific interstitial pneumonia was found in 5 and was associated with bronchiolitis obliterans in 2. There were single cases of moderately severe emphysema with bronchiolitis, bronchiolitis with muscle hypertrophy and air trapping, lymphosarcoma, eosinophilic pneumonia, probable tuberculosis, probable sarcoidosis, idiopathic pulmonary haemosiderosis, lymphomatoid Wegener's granulomatosis and probable limited form of Wegener's granulomatosis Eleven other biopsies showed some honeycombing with a variety of non-specific features and in the remaining 10 cases the changes were mild or non-specific." @default.
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- W2323978384 date "1973-01-01" @default.
- W2323978384 modified "2023-09-27" @default.
- W2323978384 title "Open lung biopsy in the diagnosis of diffuse lung disease" @default.
- W2323978384 doi "https://doi.org/10.1016/s0031-3025(16)39212-1" @default.
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