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- W2324031697 abstract "Smart, or responsive polymers can reversibly change their state of aggregation, thus switching from water-soluble to insoluble state, in response to minor changes in temperature, pH or solvent composition. Grafting of these polymers to solid surfaces imparts the surfaces with controllable wettability and adsorption behaviour. The review summarizes the theoretical models and the results of physical measurements of the conformational transitions in grafted polymer chains and polymer brushes. Primary attention is paid to the grafting density and the length and spatial arrangement of grafted chains, the role of polystyrene, organosilane or alkanethiol sublayers and their effects on adsorption of proteins and adhesion of cells. The key applications of grafted smart polymers such as cell culture and tissue engineering, cell and protein separation, biosensing and targeted drug delivery are surveyed. The bibliography includes 174 references. (Less)" @default.
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- W2324031697 date "2016-06-30" @default.
- W2324031697 modified "2023-09-25" @default.
- W2324031697 title "Smart polymers as surface modifiers for bioanalytical devices and biomaterials: theory and practice" @default.
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- W2324031697 doi "https://doi.org/10.1070/rcr4567" @default.
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