FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2324043133> ?p ?o ?g. }

• W2324043133 abstract "iven the intimate roles proteins play in health and disease,it is not surprising that during the past 20 yearsproteomics has been applied extensively to investigate humandiseases to better understand disease mechanisms/pathwaysand to define new therapeutic targets as well as novelbiomarkers for accurate diagnostics/prognostics. There is nodoubt that advancements of disease proteomics will expand thefrontiers of medicine to impact global health.This Special Issue of Journal of Proteome Research (JPR)features recent progress and advancements of proteomic studiesof human diseases, focusing on pathogenesis, pathogenicmechanisms, diagnosis, prognosis, and treatment. It includestwo reviews and 64 research articles (a total of 66 articles). Thelarge number of articles published in a single Special Issuereflects the significance and broad interest of this area.It is especially encouraging to use the occasion of this SpecialIssue to reflect on how our field has evolved. Compared withdisease proteomics articles previously published, this collectionof studies shows obvious improvements in this field as follows.First, more advanced proteomic technologies, particularlysophisticated mass spectrometry for protein characterizations,profiling, quantitative analysis, and investigations of post-translational modifications (PTMs), were used. Second, thestudy designs were more sophisticated and planned morecarefully, for example, stringent validation to confirm screeningdata sets, sufficient sample size, and suitable control groups(i.e., inclusion of diseased controls in addition to the normalcontrol). Third, functional significance of the identified proteinsor targets was confirmed in most of these studies. Finally,feasibility for clinical applications was well demonstrated, forexample, sensitivity/specificity of novel biomarkers fordiagnostics/prognostics.In addition to the two reviews that update the currentknowledge" @default.
• W2324043133 created "2016-06-24" @default.
• W2324043133 creator A5039755087 @default.
• W2324043133 creator A5046993686 @default.
• W2324043133 creator A5091140339 @default.
• W2324043133 date "2014-11-07" @default.
• W2324043133 modified "2023-09-28" @default.
• W2324043133 title "Recent Advances of Proteomics Applied to Human Diseases" @default.
• W2324043133 cites W1551209903 @default.
• W2324043133 cites W1973226334 @default.
• W2324043133 cites W1973854455 @default.
• W2324043133 cites W1975331975 @default.
• W2324043133 cites W1976766564 @default.
• W2324043133 cites W1993245113 @default.
• W2324043133 cites W1997550446 @default.
• W2324043133 cites W2003774969 @default.
• W2324043133 cites W2006958280 @default.
• W2324043133 cites W2022958334 @default.
• W2324043133 cites W2035126499 @default.
• W2324043133 cites W2036894198 @default.
• W2324043133 cites W2038927284 @default.
• W2324043133 cites W2043377280 @default.
• W2324043133 cites W2045726291 @default.
• W2324043133 cites W2045847786 @default.
• W2324043133 cites W2050605886 @default.
• W2324043133 cites W2051072127 @default.
• W2324043133 cites W2055373496 @default.
• W2324043133 cites W2055374820 @default.
• W2324043133 cites W2056394532 @default.
• W2324043133 cites W2060393222 @default.
• W2324043133 cites W2069485360 @default.
• W2324043133 cites W2071459408 @default.
• W2324043133 cites W2079757304 @default.
• W2324043133 cites W2080743371 @default.
• W2324043133 cites W2083362012 @default.
• W2324043133 cites W2089293580 @default.
• W2324043133 cites W2312720468 @default.
• W2324043133 cites W2312737724 @default.
• W2324043133 cites W2312815248 @default.
• W2324043133 cites W2313159354 @default.
• W2324043133 cites W2313648546 @default.
• W2324043133 cites W2314042823 @default.
• W2324043133 cites W2314223854 @default.
• W2324043133 cites W2314588518 @default.
• W2324043133 cites W2314602855 @default.
• W2324043133 cites W2315165778 @default.
• W2324043133 cites W2315438426 @default.
• W2324043133 cites W2315849185 @default.
• W2324043133 cites W2316076210 @default.
• W2324043133 cites W2319150273 @default.
• W2324043133 cites W2319789229 @default.
• W2324043133 cites W2320352975 @default.
• W2324043133 cites W2320474879 @default.
• W2324043133 cites W2320490619 @default.
• W2324043133 cites W2320930988 @default.
• W2324043133 cites W2321155649 @default.
• W2324043133 cites W2321774377 @default.
• W2324043133 cites W2325985150 @default.
• W2324043133 cites W2326363194 @default.
• W2324043133 cites W2327243045 @default.
• W2324043133 cites W2327662850 @default.
• W2324043133 cites W2328022522 @default.
• W2324043133 cites W2328077657 @default.
• W2324043133 cites W2328834658 @default.
• W2324043133 cites W2329041428 @default.
• W2324043133 cites W2330731414 @default.
• W2324043133 cites W2332131630 @default.
• W2324043133 cites W2333105741 @default.
• W2324043133 cites W2333939089 @default.
• W2324043133 cites W2334333112 @default.
• W2324043133 cites W2334373262 @default.
• W2324043133 cites W2335077276 @default.
• W2324043133 cites W2335711157 @default.
• W2324043133 cites W2891623477 @default.
• W2324043133 doi "https://doi.org/10.1021/pr501038g" @default.
• W2324043133 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25377741" @default.
• W2324043133 hasPublicationYear "2014" @default.
• W2324043133 type Work @default.
• W2324043133 sameAs 2324043133 @default.
• W2324043133 citedByCount "9" @default.
• W2324043133 countsByYear W23240431332015 @default.
• W2324043133 countsByYear W23240431332016 @default.
• W2324043133 countsByYear W23240431332017 @default.
• W2324043133 countsByYear W23240431332018 @default.
• W2324043133 countsByYear W23240431332019 @default.
• W2324043133 countsByYear W23240431332020 @default.
• W2324043133 countsByYear W23240431332022 @default.
• W2324043133 crossrefType "journal-article" @default.
• W2324043133 hasAuthorship W2324043133A5039755087 @default.
• W2324043133 hasAuthorship W2324043133A5046993686 @default.
• W2324043133 hasAuthorship W2324043133A5091140339 @default.
• W2324043133 hasConcept C100631289 @default.
• W2324043133 hasConcept C104317684 @default.
• W2324043133 hasConcept C104397665 @default.
• W2324043133 hasConcept C142724271 @default.
• W2324043133 hasConcept C181199279 @default.
• W2324043133 hasConcept C2522767166 @default.
• W2324043133 hasConcept C2779134260 @default.
• W2324043133 hasConcept C41008148 @default.
• W2324043133 hasConcept C46111723 @default.

• next