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- W2324176861 abstract "The effect of soy protein on the small bowel mucosa of 18 infants with acute gastroenteritis was studied. The infants were maintained on a protein hydro-lysate formula for 6–8 weeks, following which they were readmitted for soy protein challenge studies. Jejunal biopsy was performed before and 24 h after challenge. On the basis of the clinical and histological reaction to soy protein challenge, three groups were identified. Group 1 consisted of three infants who had clinical and histological reaction. There was associated depletion of mucosal enzymes, lactase, sucrase, malatase, alkaline phosphatase, and blood xylose levels. Group 2 consisted of seven infants who had histological reaction but no clinical symptoms. Two of these seven infants, however, developed clinical reaction when rechallenged with soy protein 2 and 90 days later. Following challenge, mucosal enzymes and blood xylose levels were depressed in five of the seven infants tested. Group 3 consisted of eight infants who did not have either a clinical or a histological reaction. The mucosal enzymes and blood xylose levels were not depressed in four infants tested. The present study shows that the small bowel mucosa of some young infants recovering from acute gastroenteritis remains sensitive to soy protein for a variable period of time. The feeding of soy protein to these infants may result in the persistence of mucosal damage and perpetuation of diarrhea. These findings have an important bearing in the nutritional management of infants recovering from AGE; the exclusion of soy protein from the diet of these infants, particularly during the period when the mucosa is damaged, may reduce the risk of the development of soy protein sensitive enteropathy and the attendant complication of protracted diarrhea." @default.
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- W2324176861 date "1988-01-01" @default.
- W2324176861 modified "2023-10-16" @default.
- W2324176861 title "Effect of Soy Protein on the Small Bowel Mucosa of Young Infants Recovering from Acute Gastroenteritis" @default.
- W2324176861 doi "https://doi.org/10.1097/00005176-198801000-00014" @default.
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