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• W2324334890 abstract "Event Abstract Back to Event State-dependent cortical processing: Cholinergic modulation of visual responses Neuromodulatory systems are capable of modifying cortical states by altering cell excitability and functional connectivity, but the consequences for cortical processing are not well understood. We address this issue by using silicon polytrodes to record visual cortical responses of anesthetized rats in response to stimulation of the basal forebrain cholinergic system, an important neuromodulatory system implicated in arousal and attention. We find that basal forebrain stimulation causes an mAChR-dependent decrease in between-neuron correlations across all layers of cortex, consistent with previous studies using EEG recordings. Furthermore, basal forebrain stimulation results in an increase in cortical response reliability to repeated presentations of natural movies through mechanism(s) independent of cortical mAChRs. Both the desynchronization and the improved response reliability are likely to enhance sensory coding capacity in cortex. Thus, these modifications of cortical activity by the basal forebrain may mediate changes in sensory processing during different behavioral states. Conference: Computational and systems neuroscience 2009, Salt Lake City, UT, United States, 26 Feb - 3 Mar, 2009. Presentation Type: Oral Presentation Topic: Oral Presentations Citation: (2009). State-dependent cortical processing: Cholinergic modulation of visual responses. Front. Syst. Neurosci. Conference Abstract: Computational and systems neuroscience 2009. doi: 10.3389/conf.neuro.06.2009.03.224 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 03 Feb 2009; Published Online: 03 Feb 2009. Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Google Google Scholar PubMed Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W2324334890 title "State-dependent cortical processing: Cholinergic modulation of visual responses" @default.
• W2324334890 doi "https://doi.org/10.3389/conf.neuro.06.2009.03.224" @default.
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