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• W2324379552 abstract "Cationic oligo-p-phenylene ethynylenes have shown much promise as broad-spectrum light-activated antimicrobial compounds against both Gram-positive and Gram-negative bacteria. The anionic varieties, however, have weak biocidal activity. In this study, a complex is formed between a weakly biocidal anionic oligomer and a cationic surfactant, and the effects on their biocidal activity against Gram-negative E. coli and Gram-positive S. aureus are explored. The enhancement in biocidal activity that is observed when the complex is irradiated suggests that interfacial surfactant gives the complex a net-positive charge, allowing it to associate strongly with the bacterial membrane. The results of this study demonstrate a method for the enhancement of biocidal activity of singlet-oxygen sensitizers and corroborate the use of surfactants as trans-membrane drug-delivery agents." @default.
• W2324379552 created "2016-06-24" @default.
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• W2324379552 date "2014-05-02" @default.
• W2324379552 modified "2023-09-24" @default.
• W2324379552 title "Activating the Antimicrobial Activity of an Anionic Singlet-Oxygen Sensitizer through Surfactant Complexation" @default.
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• W2324379552 doi "https://doi.org/10.1021/la501230m" @default.
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