Matches in SemOpenAlex for { <https://semopenalex.org/work/W2324390410> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2324390410 endingPage "1608" @default.
- W2324390410 startingPage "1597" @default.
- W2324390410 abstract "Cisplatinum was administered by intra-venous injection and intra-arterial injection for the treatment of oral cancer patients. The protin-bound platinum levels and non-proteinbound platinum levels in plasma were measured. As results:(1) The non-protein-bound platinum level declined rapidly following the end of administration and cleared below the measurable level within 2 hours. The mean half-life time was 29.2 minutes in intra-arterial injection, and 31.9 minutes in intra-venous injection. Larger doses of cisplatin resulted in higher plasma levels of non-protein-bound platinum, which were not dose-dependent.(2) Total platinum level decreased in a biphasic mode with a mean α-phase half-life time of 57.5 minutes in intra-arterial injection and 51.6 minutes in intra-venous injection. But no significant difference was found in the changes of plasma concentration between intra-arterial and intravenous injection methods.(3) The maximum plasma concentration and area under the curve (AUC) of non-protein-bound platinum varied in proportion to the dose per area of body surface in intra-venous injection cases. In conclusion, it is considered that the optimal method of CDDP administration should be selected not only by the higher plasma concentration and wider AUC of non-protein-bound Pt but also by the decrease of side effects and the increase of antitumor effects." @default.
- W2324390410 created "2016-06-24" @default.
- W2324390410 creator A5002381555 @default.
- W2324390410 creator A5007942711 @default.
- W2324390410 creator A5013426905 @default.
- W2324390410 creator A5015120177 @default.
- W2324390410 creator A5016422374 @default.
- W2324390410 creator A5024447636 @default.
- W2324390410 creator A5043631647 @default.
- W2324390410 creator A5083113771 @default.
- W2324390410 date "1988-01-01" @default.
- W2324390410 modified "2023-10-16" @default.
- W2324390410 title "Pharmacokinetics of cis-dichlorodiamine-platinum(II) in patients with oral cancer." @default.
- W2324390410 cites W1582307411 @default.
- W2324390410 cites W1647111392 @default.
- W2324390410 cites W1991463182 @default.
- W2324390410 cites W2012733679 @default.
- W2324390410 cites W2109089720 @default.
- W2324390410 cites W2266243075 @default.
- W2324390410 cites W2414747217 @default.
- W2324390410 cites W2415857393 @default.
- W2324390410 cites W2417354031 @default.
- W2324390410 cites W2418932949 @default.
- W2324390410 cites W2465343762 @default.
- W2324390410 cites W2468707786 @default.
- W2324390410 cites W2511915483 @default.
- W2324390410 cites W5922547 @default.
- W2324390410 cites W614456250 @default.
- W2324390410 doi "https://doi.org/10.5794/jjoms.34.1597" @default.
- W2324390410 hasPublicationYear "1988" @default.
- W2324390410 type Work @default.
- W2324390410 sameAs 2324390410 @default.
- W2324390410 citedByCount "0" @default.
- W2324390410 crossrefType "journal-article" @default.
- W2324390410 hasAuthorship W2324390410A5002381555 @default.
- W2324390410 hasAuthorship W2324390410A5007942711 @default.
- W2324390410 hasAuthorship W2324390410A5013426905 @default.
- W2324390410 hasAuthorship W2324390410A5015120177 @default.
- W2324390410 hasAuthorship W2324390410A5016422374 @default.
- W2324390410 hasAuthorship W2324390410A5024447636 @default.
- W2324390410 hasAuthorship W2324390410A5043631647 @default.
- W2324390410 hasAuthorship W2324390410A5083113771 @default.
- W2324390410 hasBestOaLocation W23243904101 @default.
- W2324390410 hasConcept C112705442 @default.
- W2324390410 hasConcept C126322002 @default.
- W2324390410 hasConcept C126894567 @default.
- W2324390410 hasConcept C138944611 @default.
- W2324390410 hasConcept C161790260 @default.
- W2324390410 hasConcept C185592680 @default.
- W2324390410 hasConcept C2776694085 @default.
- W2324390410 hasConcept C2777501473 @default.
- W2324390410 hasConcept C2778239845 @default.
- W2324390410 hasConcept C3941253 @default.
- W2324390410 hasConcept C42219234 @default.
- W2324390410 hasConcept C43044207 @default.
- W2324390410 hasConcept C518104683 @default.
- W2324390410 hasConcept C55493867 @default.
- W2324390410 hasConcept C71924100 @default.
- W2324390410 hasConceptScore W2324390410C112705442 @default.
- W2324390410 hasConceptScore W2324390410C126322002 @default.
- W2324390410 hasConceptScore W2324390410C126894567 @default.
- W2324390410 hasConceptScore W2324390410C138944611 @default.
- W2324390410 hasConceptScore W2324390410C161790260 @default.
- W2324390410 hasConceptScore W2324390410C185592680 @default.
- W2324390410 hasConceptScore W2324390410C2776694085 @default.
- W2324390410 hasConceptScore W2324390410C2777501473 @default.
- W2324390410 hasConceptScore W2324390410C2778239845 @default.
- W2324390410 hasConceptScore W2324390410C3941253 @default.
- W2324390410 hasConceptScore W2324390410C42219234 @default.
- W2324390410 hasConceptScore W2324390410C43044207 @default.
- W2324390410 hasConceptScore W2324390410C518104683 @default.
- W2324390410 hasConceptScore W2324390410C55493867 @default.
- W2324390410 hasConceptScore W2324390410C71924100 @default.
- W2324390410 hasIssue "8" @default.
- W2324390410 hasLocation W23243904101 @default.
- W2324390410 hasOpenAccess W2324390410 @default.
- W2324390410 hasPrimaryLocation W23243904101 @default.
- W2324390410 hasRelatedWork W1505415130 @default.
- W2324390410 hasRelatedWork W1979295668 @default.
- W2324390410 hasRelatedWork W1991463182 @default.
- W2324390410 hasRelatedWork W2012287281 @default.
- W2324390410 hasRelatedWork W2057051402 @default.
- W2324390410 hasRelatedWork W2090850966 @default.
- W2324390410 hasRelatedWork W2324390410 @default.
- W2324390410 hasRelatedWork W2408583735 @default.
- W2324390410 hasRelatedWork W2410694577 @default.
- W2324390410 hasRelatedWork W2778370295 @default.
- W2324390410 hasVolume "34" @default.
- W2324390410 isParatext "false" @default.
- W2324390410 isRetracted "false" @default.
- W2324390410 magId "2324390410" @default.
- W2324390410 workType "article" @default.