FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2324456616> ?p ?o ?g. }

• W2324456616 endingPage "127" @default.
• W2324456616 startingPage "122" @default.
• W2324456616 abstract "Fo Shou San (FSS) is an ancient herbal decoction composed of Angelicae Sinensis Radix (ASR; Danggui) and Chuanxiong Rhizoma (CR; Chuanxiong) in a ratio of 3 : 2. FSS is mainly prescribed for patients having a deficiency of blood supply, and it indeed has been shown to stimulate the production of erythropoietin (EPO) in cultured cells. In order to reveal the mechanism of this FSS-induced EPO gene expression, the upstream regulatory cascade, via hypoxia-induced signaling, was revealed here in cultured hepatocellular carcinoma cell line Hep3B. The induction of EPO gene expression, triggered by FSS, was revealed in cultured hepatocytes by: (i) the increase of EPO mRNA; and (ii) the activation of the hypoxia response element (HRE), an upstream regulator of the EPO gene. The FSS-induced EPO gene expression was triggered by an increased expression of hypoxia-inducible factor-1α (HIF-1α) protein; however, the mRNA expression of HIF-1α was not altered by the treatment of FSS. The increased HIF-1α was a result of reduced protein degradation after the FSS treatment. The current results therefore provide one of the molecular mechanisms of this ancient herbal decoction for its hematopoietic function." @default.
• W2324456616 created "2016-06-24" @default.
• W2324456616 creator A5006355763 @default.
• W2324456616 creator A5019266089 @default.
• W2324456616 creator A5022454719 @default.
• W2324456616 creator A5024361918 @default.
• W2324456616 creator A5030281534 @default.
• W2324456616 creator A5045896435 @default.
• W2324456616 creator A5048888048 @default.
• W2324456616 creator A5055029086 @default.
• W2324456616 creator A5055673163 @default.
• W2324456616 creator A5061942569 @default.
• W2324456616 creator A5079138523 @default.
• W2324456616 creator A5089844492 @default.
• W2324456616 date "2011-11-17" @default.
• W2324456616 modified "2023-10-01" @default.
• W2324456616 title "Fo Shou San, an Ancient Herbal Decoction Prepared from Angelicae Sinensis Radix and Chuanxiong Rhizoma, Induces Erythropoietin Expression: A Signaling Mediated by the Reduced Degradation of Hypoxia-Inducible Factor in Cultured Liver Cells" @default.
• W2324456616 cites W1493841569 @default.
• W2324456616 cites W1582693243 @default.
• W2324456616 cites W1591222350 @default.
• W2324456616 cites W1967275315 @default.
• W2324456616 cites W1991122654 @default.
• W2324456616 cites W1991454225 @default.
• W2324456616 cites W1999840084 @default.
• W2324456616 cites W2000189128 @default.
• W2324456616 cites W2005538515 @default.
• W2324456616 cites W2008264589 @default.
• W2324456616 cites W2013215312 @default.
• W2324456616 cites W2016995575 @default.
• W2324456616 cites W2019289959 @default.
• W2324456616 cites W2032337032 @default.
• W2324456616 cites W2042755979 @default.
• W2324456616 cites W2051419174 @default.
• W2324456616 cites W2056731363 @default.
• W2324456616 cites W2056850109 @default.
• W2324456616 cites W2062512166 @default.
• W2324456616 cites W2062706326 @default.
• W2324456616 cites W2065642253 @default.
• W2324456616 cites W2085609942 @default.
• W2324456616 cites W2120228115 @default.
• W2324456616 cites W2137333423 @default.
• W2324456616 cites W2144625075 @default.
• W2324456616 cites W2153771223 @default.
• W2324456616 cites W2157705760 @default.
• W2324456616 cites W2158794894 @default.
• W2324456616 cites W2293879350 @default.
• W2324456616 cites W882813942 @default.
• W2324456616 doi "https://doi.org/10.1055/s-0031-1280356" @default.
• W2324456616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22095261" @default.
• W2324456616 hasPublicationYear "2011" @default.
• W2324456616 type Work @default.
• W2324456616 sameAs 2324456616 @default.
• W2324456616 citedByCount "7" @default.
• W2324456616 countsByYear W23244566162013 @default.
• W2324456616 countsByYear W23244566162014 @default.
• W2324456616 countsByYear W23244566162017 @default.
• W2324456616 countsByYear W23244566162018 @default.
• W2324456616 countsByYear W23244566162023 @default.
• W2324456616 crossrefType "journal-article" @default.
• W2324456616 hasAuthorship W2324456616A5006355763 @default.
• W2324456616 hasAuthorship W2324456616A5019266089 @default.
• W2324456616 hasAuthorship W2324456616A5022454719 @default.
• W2324456616 hasAuthorship W2324456616A5024361918 @default.
• W2324456616 hasAuthorship W2324456616A5030281534 @default.
• W2324456616 hasAuthorship W2324456616A5045896435 @default.
• W2324456616 hasAuthorship W2324456616A5048888048 @default.
• W2324456616 hasAuthorship W2324456616A5055029086 @default.
• W2324456616 hasAuthorship W2324456616A5055673163 @default.
• W2324456616 hasAuthorship W2324456616A5061942569 @default.
• W2324456616 hasAuthorship W2324456616A5079138523 @default.
• W2324456616 hasAuthorship W2324456616A5089844492 @default.
• W2324456616 hasConcept C104317684 @default.
• W2324456616 hasConcept C109159458 @default.
• W2324456616 hasConcept C134018914 @default.
• W2324456616 hasConcept C142724271 @default.
• W2324456616 hasConcept C150194340 @default.
• W2324456616 hasConcept C160450060 @default.
• W2324456616 hasConcept C178790620 @default.
• W2324456616 hasConcept C185592680 @default.
• W2324456616 hasConcept C188947578 @default.
• W2324456616 hasConcept C190409667 @default.
• W2324456616 hasConcept C204787440 @default.
• W2324456616 hasConcept C2778534260 @default.
• W2324456616 hasConcept C2779454681 @default.
• W2324456616 hasConcept C28328180 @default.
• W2324456616 hasConcept C540031477 @default.
• W2324456616 hasConcept C55493867 @default.
• W2324456616 hasConcept C556039675 @default.
• W2324456616 hasConcept C71924100 @default.
• W2324456616 hasConcept C7836513 @default.
• W2324456616 hasConcept C86803240 @default.
• W2324456616 hasConcept C95444343 @default.
• W2324456616 hasConcept C98274493 @default.
• W2324456616 hasConceptScore W2324456616C104317684 @default.
• W2324456616 hasConceptScore W2324456616C109159458 @default.
• W2324456616 hasConceptScore W2324456616C134018914 @default.
• W2324456616 hasConceptScore W2324456616C142724271 @default.
• W2324456616 hasConceptScore W2324456616C150194340 @default.

• next