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- W2324456875 abstract "Copyright: © 2014 de Souza ME, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Biofilms are high degree organization communities where microorganisms form a structured, coordinated and functional thin layer [1]. The biofilm production is a successful strategy for microbial survival and infection establishment. The host defense mechanisms and the antimicrobial responses are very impaired against the microorganisms inhabiting the biofilm [2]. This resistance may be related to the antimicrobial penetration difficulty by the cell wall composed (extracellular polymeric substances such as EPS). Such factor enables unlimited dissemination and expression of resistance genes with phenotypic changes of microorganisms in the biofilm [1]. In addition, microorganisms in the biofilm are mostly in their stationary phase, hindering the action of betalactam drugs." @default.
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- W2324456875 date "2014-01-01" @default.
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- W2324456875 title "Antibiofilm Applications of Nanotechnology" @default.
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- W2324456875 doi "https://doi.org/10.4172/2165-8056.1000e117" @default.
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