FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2324461719> ?p ?o ?g. }

• W2324461719 endingPage "1477" @default.
• W2324461719 startingPage "1470" @default.
• W2324461719 abstract "Abstract Tenascin-C (TN-C) is an extracellular matrix glycoprotein markedly upregulated during liver fibrosis. The study is performed to explore the role of TN-C during the growth and activation of hepatic stellate cells (HSCs). We found that TN-C was accumulated accompanying with the HSC activation. Our data on cell migration assay revealed that the rTN-C treatment enhanced HSC migration in a dose- and time-dependent manner, but did not influence their proliferation. HSCs transfected with pTARGET-TN-C overexpression vector displayed increased the type I collagen (Col I) production. TN-C overexpression enhanced the process of HSC activation through TGF-β1 signaling. Moreover, the anti-α9β1 integrin antibody treatment blocked the TN-C-driven Col I increase in rat HSCs. Collectively, TN-C had a positive role in activation of HSCs mediated by TGF-β1 and α9β1 integrin, manifesting elevation of Col I production and promotion of cell migration. Our results provide a potential insight for the therapy of hepatic fibrosis." @default.
• W2324461719 created "2016-06-24" @default.
• W2324461719 creator A5018406495 @default.
• W2324461719 creator A5024711370 @default.
• W2324461719 creator A5040296857 @default.
• W2324461719 creator A5048859497 @default.
• W2324461719 creator A5061757687 @default.
• W2324461719 creator A5077660562 @default.
• W2324461719 creator A5081624359 @default.
• W2324461719 date "2016-08-02" @default.
• W2324461719 modified "2023-09-24" @default.
• W2324461719 title "Tenascin-C promotes migration of hepatic stellate cells and production of type I collagen" @default.
• W2324461719 cites W130577457 @default.
• W2324461719 cites W1491619495 @default.
• W2324461719 cites W1532402805 @default.
• W2324461719 cites W1607359031 @default.
• W2324461719 cites W1906235443 @default.
• W2324461719 cites W1967895142 @default.
• W2324461719 cites W1969604127 @default.
• W2324461719 cites W1973552842 @default.
• W2324461719 cites W1986980150 @default.
• W2324461719 cites W1991572445 @default.
• W2324461719 cites W1993177993 @default.
• W2324461719 cites W1995212212 @default.
• W2324461719 cites W2005270729 @default.
• W2324461719 cites W2006111363 @default.
• W2324461719 cites W2007405153 @default.
• W2324461719 cites W2016498524 @default.
• W2324461719 cites W2041587548 @default.
• W2324461719 cites W2041911908 @default.
• W2324461719 cites W2056117553 @default.
• W2324461719 cites W2057692840 @default.
• W2324461719 cites W2071817077 @default.
• W2324461719 cites W2077962618 @default.
• W2324461719 cites W2104116192 @default.
• W2324461719 cites W2135223800 @default.
• W2324461719 cites W2147692406 @default.
• W2324461719 cites W2163036793 @default.
• W2324461719 cites W2171930491 @default.
• W2324461719 cites W2487402464 @default.
• W2324461719 cites W2586366027 @default.
• W2324461719 cites W4252677148 @default.
• W2324461719 doi "https://doi.org/10.1080/09168451.2016.1165600" @default.
• W2324461719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27031437" @default.
• W2324461719 hasPublicationYear "2016" @default.
• W2324461719 type Work @default.
• W2324461719 sameAs 2324461719 @default.
• W2324461719 citedByCount "9" @default.
• W2324461719 countsByYear W23244617192017 @default.
• W2324461719 countsByYear W23244617192018 @default.
• W2324461719 countsByYear W23244617192020 @default.
• W2324461719 countsByYear W23244617192021 @default.
• W2324461719 countsByYear W23244617192022 @default.
• W2324461719 crossrefType "journal-article" @default.
• W2324461719 hasAuthorship W2324461719A5018406495 @default.
• W2324461719 hasAuthorship W2324461719A5024711370 @default.
• W2324461719 hasAuthorship W2324461719A5040296857 @default.
• W2324461719 hasAuthorship W2324461719A5048859497 @default.
• W2324461719 hasAuthorship W2324461719A5061757687 @default.
• W2324461719 hasAuthorship W2324461719A5077660562 @default.
• W2324461719 hasAuthorship W2324461719A5081624359 @default.
• W2324461719 hasBestOaLocation W23244617191 @default.
• W2324461719 hasConcept C104317684 @default.
• W2324461719 hasConcept C117961784 @default.
• W2324461719 hasConcept C126322002 @default.
• W2324461719 hasConcept C127561419 @default.
• W2324461719 hasConcept C134018914 @default.
• W2324461719 hasConcept C137738243 @default.
• W2324461719 hasConcept C1491633281 @default.
• W2324461719 hasConcept C153911025 @default.
• W2324461719 hasConcept C176891718 @default.
• W2324461719 hasConcept C185592680 @default.
• W2324461719 hasConcept C189165786 @default.
• W2324461719 hasConcept C195687474 @default.
• W2324461719 hasConcept C2780559512 @default.
• W2324461719 hasConcept C2780644872 @default.
• W2324461719 hasConcept C2993667909 @default.
• W2324461719 hasConcept C502942594 @default.
• W2324461719 hasConcept C54009773 @default.
• W2324461719 hasConcept C55493867 @default.
• W2324461719 hasConcept C71924100 @default.
• W2324461719 hasConcept C86492073 @default.
• W2324461719 hasConcept C86803240 @default.
• W2324461719 hasConcept C95444343 @default.
• W2324461719 hasConceptScore W2324461719C104317684 @default.
• W2324461719 hasConceptScore W2324461719C117961784 @default.
• W2324461719 hasConceptScore W2324461719C126322002 @default.
• W2324461719 hasConceptScore W2324461719C127561419 @default.
• W2324461719 hasConceptScore W2324461719C134018914 @default.
• W2324461719 hasConceptScore W2324461719C137738243 @default.
• W2324461719 hasConceptScore W2324461719C1491633281 @default.
• W2324461719 hasConceptScore W2324461719C153911025 @default.
• W2324461719 hasConceptScore W2324461719C176891718 @default.
• W2324461719 hasConceptScore W2324461719C185592680 @default.
• W2324461719 hasConceptScore W2324461719C189165786 @default.
• W2324461719 hasConceptScore W2324461719C195687474 @default.
• W2324461719 hasConceptScore W2324461719C2780559512 @default.
• W2324461719 hasConceptScore W2324461719C2780644872 @default.

• next