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• W2324542009 abstract "非虚血性心室頻拍 (以下VT) 例においてエントレーメント現象を利用しIa群抗不整脈薬のリエントリー回路への定量的評価を試みた.VTはいずれもプロカインアミド (以下PA) の投与前後で誘発され, 同一QRS波形を示し, VT中の頻回刺激でエントレーメント現象が認められた.リエントリー回路を介する順行性伝導時間 (以下CTo) はエントレーメント中の刺激から最早期興奮部位までの時間とし, 逆行性伝導時間 (以下CTa) は洞調律時の両者間の伝導時間とした.VTを停止させる最長の刺激周期をBlook CLとし, リエントリー回路外の心筋の不応期 (以下ERP) を刺激部位で求めた.PA投与後, VT周期とCToは有意に延長し, 両者の変化は高い相関を示した.しかし, CToの変化はCTaの変化に比べ有意に大で, PAは緩徐伝導路により選択的に作用すると考えられた.Block CLも有意に延長したが, 正常心筋でのERPの変化はそれより有意に小であった.PAは緩徐伝導路の伝導速度を低下させ伝導途絶をきたす周期を延長させるが, この作用はより緩徐伝導路に選択的と考えられた." @default.
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• W2324542009 date "1993-01-01" @default.
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• W2324542009 title "The effects of class Ia drug on the reentrant circuit of ventricular tachycardia." @default.
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• W2324542009 doi "https://doi.org/10.5105/jse.13.728" @default.
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