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- W2324738807 abstract "We report that the continuous assembly of polymers (CAP) approach, mediated by ring-opening metathesis polymerization (ROMP), is a facile and versatile technology to prepare engineered nanocoatings for various biomedical applications. Low-fouling coatings on particles were obtained by the formation of multicompositional, layered films via simple and efficient tandem CAPROMP processes that are analogous to chain extension reactions. In addition, the CAPROMP approach allows for the efficient postfunctionalization of the CAP films with bioactive moieties via cross-metathesis reactions between the surface-immobilized catalysts and symmetrical alkene derivatives. The combined features of the CAPROMP approach (i.e., versatile polymer selection and facile functionalization) allow for the fabrication and surface modification of various types of polymer films, including those with intrinsic protein-repellent properties and selective protein recognition capabilities. This study highlights the various types of advanced coatings and materials that the CAP approach can be used to generate, which may be useful for biomedical applications." @default.
- W2324738807 created "2016-06-24" @default.
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- W2324738807 date "2013-07-10" @default.
- W2324738807 modified "2023-10-17" @default.
- W2324738807 title "Low-Fouling, Biospecific Films Prepared by the Continuous Assembly of Polymers" @default.
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- W2324738807 doi "https://doi.org/10.1021/bm400680d" @default.
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