Matches in SemOpenAlex for { <https://semopenalex.org/work/W2324751011> ?p ?o ?g. }
- W2324751011 endingPage "L969" @default.
- W2324751011 startingPage "L959" @default.
- W2324751011 abstract "Bronchopulmonary dysplasia (BPD) is an important lung developmental pathophysiology that affects many premature infants each year. Newborn animal models employing both premature and term animals have been used over the years to study various components of BPD. This review describes some of the neonatal rabbit studies that have contributed to the understanding of BPD, including those using term newborn hyperoxia exposure models, premature hyperoxia models, and a term newborn hyperoxia model with recovery in moderate hyperoxia, all designed to emulate aspects of BPD in human infants. Some investigators perturbed these models to include exposure to neonatal infection/inflammation or postnatal malnutrition. The similarities to lung injury in human premature infants include an acute inflammatory response with the production of cytokines, chemokines, and growth factors that have been implicated in human disease, abnormal pulmonary function, disordered lung architecture, and alveolar simplification, development of fibrosis, and abnormal vascular growth factor expression. Neonatal rabbit models have the drawback of limited access to reagents as well as the lack of readily available transgenic models but, unlike smaller rodent models, are able to be manipulated easily and are significantly less expensive than larger animal models." @default.
- W2324751011 created "2016-06-24" @default.
- W2324751011 creator A5009698775 @default.
- W2324751011 creator A5068833247 @default.
- W2324751011 date "2014-12-15" @default.
- W2324751011 modified "2023-10-18" @default.
- W2324751011 title "Animal models of bronchopulmonary dysplasia. The preterm and term rabbit models" @default.
- W2324751011 cites W126408878 @default.
- W2324751011 cites W1610638937 @default.
- W2324751011 cites W1810046561 @default.
- W2324751011 cites W1964294676 @default.
- W2324751011 cites W1966650689 @default.
- W2324751011 cites W1969277474 @default.
- W2324751011 cites W1969292870 @default.
- W2324751011 cites W1971097876 @default.
- W2324751011 cites W1973076790 @default.
- W2324751011 cites W1973593141 @default.
- W2324751011 cites W1974387205 @default.
- W2324751011 cites W1974421375 @default.
- W2324751011 cites W1977452999 @default.
- W2324751011 cites W1979714315 @default.
- W2324751011 cites W1980664389 @default.
- W2324751011 cites W1984149072 @default.
- W2324751011 cites W1985241778 @default.
- W2324751011 cites W1986200620 @default.
- W2324751011 cites W1987868867 @default.
- W2324751011 cites W1989700111 @default.
- W2324751011 cites W1989728523 @default.
- W2324751011 cites W1997557154 @default.
- W2324751011 cites W2001988926 @default.
- W2324751011 cites W2003758264 @default.
- W2324751011 cites W2006500041 @default.
- W2324751011 cites W2006850047 @default.
- W2324751011 cites W2010630815 @default.
- W2324751011 cites W2011050399 @default.
- W2324751011 cites W2013196779 @default.
- W2324751011 cites W2020887727 @default.
- W2324751011 cites W2021012065 @default.
- W2324751011 cites W2024962699 @default.
- W2324751011 cites W2025283490 @default.
- W2324751011 cites W2026193967 @default.
- W2324751011 cites W2026524338 @default.
- W2324751011 cites W2028384276 @default.
- W2324751011 cites W2030270574 @default.
- W2324751011 cites W2030682755 @default.
- W2324751011 cites W2034477228 @default.
- W2324751011 cites W2035649809 @default.
- W2324751011 cites W2035729757 @default.
- W2324751011 cites W2035776773 @default.
- W2324751011 cites W2036202422 @default.
- W2324751011 cites W2040044700 @default.
- W2324751011 cites W2044353814 @default.
- W2324751011 cites W2044823299 @default.
- W2324751011 cites W2046458107 @default.
- W2324751011 cites W2049058842 @default.
- W2324751011 cites W2052050881 @default.
- W2324751011 cites W2052509247 @default.
- W2324751011 cites W2054835614 @default.
- W2324751011 cites W2058079998 @default.
- W2324751011 cites W2061819680 @default.
- W2324751011 cites W2067410074 @default.
- W2324751011 cites W2069241279 @default.
- W2324751011 cites W2070971583 @default.
- W2324751011 cites W2077052411 @default.
- W2324751011 cites W2077673146 @default.
- W2324751011 cites W2078631643 @default.
- W2324751011 cites W2079505297 @default.
- W2324751011 cites W2081581080 @default.
- W2324751011 cites W2083653480 @default.
- W2324751011 cites W2083899656 @default.
- W2324751011 cites W2084616912 @default.
- W2324751011 cites W2086383563 @default.
- W2324751011 cites W2089288497 @default.
- W2324751011 cites W2089820963 @default.
- W2324751011 cites W2090645678 @default.
- W2324751011 cites W2091833861 @default.
- W2324751011 cites W2092991088 @default.
- W2324751011 cites W2093079245 @default.
- W2324751011 cites W2098306584 @default.
- W2324751011 cites W2100293996 @default.
- W2324751011 cites W2103911567 @default.
- W2324751011 cites W2109011196 @default.
- W2324751011 cites W2110702168 @default.
- W2324751011 cites W2115621749 @default.
- W2324751011 cites W2116816667 @default.
- W2324751011 cites W2118997818 @default.
- W2324751011 cites W2120564205 @default.
- W2324751011 cites W2125769209 @default.
- W2324751011 cites W2126289907 @default.
- W2324751011 cites W2126700069 @default.
- W2324751011 cites W2128838829 @default.
- W2324751011 cites W2128895949 @default.
- W2324751011 cites W2129287230 @default.
- W2324751011 cites W2133870560 @default.
- W2324751011 cites W2135951260 @default.
- W2324751011 cites W2138960272 @default.
- W2324751011 cites W2142210315 @default.
- W2324751011 cites W2142919707 @default.