FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2324796865> ?p ?o ?g. }

• W2324796865 endingPage "550" @default.
• W2324796865 startingPage "542" @default.
• W2324796865 abstract "Fibrin degradation results in the formation of fibrin degradation products (FDPs) of different molecular weights, which include D-dimer. Commercial D-dimer assays recognize multiple forms of FDP with different specificity. As a result, the absence of an international D-dimer standard and the marked discrepancy in the D-dimer values in the same samples measured by assays from different manufacturers have become the primary problems that clinicians face in the D-dimer determination. We consider that an assay with equal specificity to all FDP forms regardless of their molecular weights could help to solve these problems. We aimed to produce mAbs that could equally recognize high-molecular-weight FDP (HMW FDP) and D-dimer. mAbs against D-dimer were produced. The HMW FDP/D-dimer ratios in plasma samples were analyzed following protein separation by gel filtration using the developed fluoroimmunoassay. A sandwich immunoassay with equal specificity to HMW FDP and D-dimer was developed and applied to determine HMW FDP/D-dimer ratios in patients with different diseases. Although the HMW FDP levels prevailed in thrombotic patients, the FDP and D-dimer levels were comparable in septic patients. Meanwhile, the D-dimer levels often exceeded the HMW FDP levels in patients who had undergone surgery. The ‘D-dimer’ levels that were detected by different assays also varied greatly depending on the assay specificities to FDP and D-dimer. Our findings show that the introduction of assays with equal specificities to FDP and D-dimer in clinical practice is a possible way of standardizing D-dimer measurements." @default.
• W2324796865 created "2016-06-24" @default.
• W2324796865 creator A5007668914 @default.
• W2324796865 creator A5016505766 @default.
• W2324796865 creator A5025952507 @default.
• W2324796865 creator A5029974420 @default.
• W2324796865 creator A5038314535 @default.
• W2324796865 creator A5040968339 @default.
• W2324796865 creator A5056323776 @default.
• W2324796865 date "2016-07-01" @default.
• W2324796865 modified "2023-09-26" @default.
• W2324796865 title "Monoclonal antibodies with equal specificity to D-dimer and high-molecular-weight fibrin degradation products" @default.
• W2324796865 cites W10170936 @default.
• W2324796865 cites W1629966220 @default.
• W2324796865 cites W174419108 @default.
• W2324796865 cites W1814751417 @default.
• W2324796865 cites W1892541075 @default.
• W2324796865 cites W1970236726 @default.
• W2324796865 cites W1970559777 @default.
• W2324796865 cites W1970932627 @default.
• W2324796865 cites W1971228807 @default.
• W2324796865 cites W1971846021 @default.
• W2324796865 cites W2014569258 @default.
• W2324796865 cites W2021498999 @default.
• W2324796865 cites W2021988356 @default.
• W2324796865 cites W2025358191 @default.
• W2324796865 cites W2033165482 @default.
• W2324796865 cites W2039558934 @default.
• W2324796865 cites W2042302341 @default.
• W2324796865 cites W2048473092 @default.
• W2324796865 cites W2053500608 @default.
• W2324796865 cites W2055748057 @default.
• W2324796865 cites W2056324313 @default.
• W2324796865 cites W2065835803 @default.
• W2324796865 cites W2073072707 @default.
• W2324796865 cites W2074979096 @default.
• W2324796865 cites W2077340508 @default.
• W2324796865 cites W2079183569 @default.
• W2324796865 cites W2086473663 @default.
• W2324796865 cites W2087431743 @default.
• W2324796865 cites W2102157369 @default.
• W2324796865 cites W2119736160 @default.
• W2324796865 cites W2132470959 @default.
• W2324796865 cites W2141780194 @default.
• W2324796865 cites W2143369052 @default.
• W2324796865 cites W2143504376 @default.
• W2324796865 cites W2148879334 @default.
• W2324796865 cites W2152717466 @default.
• W2324796865 cites W2266911869 @default.
• W2324796865 cites W2407806119 @default.
• W2324796865 cites W2418234813 @default.
• W2324796865 cites W4365787275 @default.
• W2324796865 cites W4378211146 @default.
• W2324796865 cites W70104120 @default.
• W2324796865 doi "https://doi.org/10.1097/mbc.0000000000000453" @default.
• W2324796865 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4935535" @default.
• W2324796865 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26656897" @default.
• W2324796865 hasPublicationYear "2016" @default.
• W2324796865 type Work @default.
• W2324796865 sameAs 2324796865 @default.
• W2324796865 citedByCount "14" @default.
• W2324796865 countsByYear W23247968652017 @default.
• W2324796865 countsByYear W23247968652018 @default.
• W2324796865 countsByYear W23247968652019 @default.
• W2324796865 countsByYear W23247968652020 @default.
• W2324796865 countsByYear W23247968652021 @default.
• W2324796865 countsByYear W23247968652023 @default.
• W2324796865 crossrefType "journal-article" @default.
• W2324796865 hasAuthorship W2324796865A5007668914 @default.
• W2324796865 hasAuthorship W2324796865A5016505766 @default.
• W2324796865 hasAuthorship W2324796865A5025952507 @default.
• W2324796865 hasAuthorship W2324796865A5029974420 @default.
• W2324796865 hasAuthorship W2324796865A5038314535 @default.
• W2324796865 hasAuthorship W2324796865A5040968339 @default.
• W2324796865 hasAuthorship W2324796865A5056323776 @default.
• W2324796865 hasBestOaLocation W23247968652 @default.
• W2324796865 hasConcept C126322002 @default.
• W2324796865 hasConcept C159654299 @default.
• W2324796865 hasConcept C178790620 @default.
• W2324796865 hasConcept C185592680 @default.
• W2324796865 hasConcept C203014093 @default.
• W2324796865 hasConcept C2779519742 @default.
• W2324796865 hasConcept C2779546866 @default.
• W2324796865 hasConcept C2780420688 @default.
• W2324796865 hasConcept C43617362 @default.
• W2324796865 hasConcept C54173615 @default.
• W2324796865 hasConcept C542903549 @default.
• W2324796865 hasConcept C71924100 @default.
• W2324796865 hasConceptScore W2324796865C126322002 @default.
• W2324796865 hasConceptScore W2324796865C159654299 @default.
• W2324796865 hasConceptScore W2324796865C178790620 @default.
• W2324796865 hasConceptScore W2324796865C185592680 @default.
• W2324796865 hasConceptScore W2324796865C203014093 @default.
• W2324796865 hasConceptScore W2324796865C2779519742 @default.
• W2324796865 hasConceptScore W2324796865C2779546866 @default.
• W2324796865 hasConceptScore W2324796865C2780420688 @default.
• W2324796865 hasConceptScore W2324796865C43617362 @default.
• W2324796865 hasConceptScore W2324796865C54173615 @default.

• next