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- W2324871338 abstract "Publisher Summary This chapter discusses a study to analyze facets of intracellular regulation of meiosis and mitosis. In the study, the response of meiotic and mitotic cells to azaguanine, chloramphenicol, ethionine, and 5-methyltryptophan were studied. It was shown that these reagents are capable of interfering with the progress of the two cycles, the type of interference depending upon the stage of the cycle at which the inhibitors reach the cell. In the case of meiosis, most of the major disruptions observed could occur by inhibiting synthesis of protein up to pachytene or diplotene. These included failure of spindle action, arrest of second division, inhibition of cytokinesis, aberrant wall synthesis, and alterations in chromosome morphology. In the case of mitosis, the study was mainly concerned with a single enzyme—thymidine phosphorylase—and it was shown that reagents that inhibit protein synthesis also inhibit the appearance of that enzyme provided that the reagent is applied at least 1 day prior to its normal appearance." @default.
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- W2324871338 date "1963-01-01" @default.
- W2324871338 modified "2023-10-16" @default.
- W2324871338 title "FACETS OF INTRACELLULAR REGULATION OF MEIOSIS AND MITOSIS1" @default.
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