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- W2324880007 abstract "In this study, the antibacterial and antioxidative activities of Epimedium koreanum Nakai were investigated for applications as cosmetic ingredients. Minimum inhibitory concentrations (MICs) of fraction-bacterium, that showed high antibacterial activity from disc diffusion assay on human skin pathogens, were tested. The ethyl acetate fraction on Staphylococcus aureus, Bacillus subtilis, Propionibacterium acnes and 50% ethanol extract on S. aureus exhibited higher antibacterial activities than methyl paraben, well known as a preservative. The DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging activities of 3 fractions of E. koreanum Nakai were lower than (+)--tocopherol, known as a typical antioxidant. From the results of the scavenging activities of various ROS generated in systems (), 50% ethanol extract () and aglycone fraction () showed high activities similar to L-ascorbic acid (), used as reference. The cellular protective effects () on photohemolysis by generated by photosensitization reaction were tested. The cellular protective effect of 50% ethanol extract ( min) was similar to (+)--tocopherol ( min), used as reference. In particular, the of aglycone fraction results were min. This is a high cellular protective effect, more than 4 times that of (+)--tocopherol. These results indicate that E. koreanum Nakai extract, and its fractions, could be utilized as a cosmetic ingredient possessing antibacterial and antioxidative activities." @default.
- W2324880007 created "2016-06-24" @default.
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- W2324880007 date "2013-09-01" @default.
- W2324880007 modified "2023-09-25" @default.
- W2324880007 title "Antibacterial and Antioxidative Activities of Epimedium koreanum Nakai Extracts" @default.
- W2324880007 doi "https://doi.org/10.4014/kjmb.1212.12001" @default.
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