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• W2324881013 abstract "PURPOSE: The purpose of this study was to determine the effect of oral sucrose solution on pain responses of neonates to arterial puncture compared with neonates who did not receive a sucrose solution. SUBJECTS: Convenience sample of 47 neonates, 31 to 35 weeks' gestational age. DESIGN: Double-blind, randomized controlled trial. MAIN OUTCOME MEASURE: Changes in pain response during and after an arterial puncture. METHODS: Infants were randomly assigned to receive a 24% sucrose solution or usual care (comfort measures only) 2 minutes before an arterial puncture. Pain, heart rate, and oxygen saturation were measured before, during, and after an arterial puncture. Chi-square analysis was used to determine group differences, with P < .05 considered significant. RESULTS: Forty-seven subjects were studied during arterial puncture (sucrose, 24; no sucrose, 23). Neonates receiving sucrose solution had significantly less crying than the no sucrose group, both during and immediately after an arterial puncture (P = .006 and .022, respectively). No significant changes in other pain subscales, heart rate, or oxygen saturation were found during or after the arterial puncture (P > .05). CONCLUSION: This study found a significant reduction in the crying subscale of the Neonatal Infant Pain subscale immediately after the introduction of an arterial needle in neonates receiving a 24% sucrose solution, compared with those who did not receive sucrose solution. While prior studies found a similar reduction in pain scores after heel and venipuncture needlesticks, this is the first study evaluating a high concentration of oral sucrose to blunt the pain associated with an arterial puncture." @default.
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• W2324881013 date "2011-12-01" @default.
• W2324881013 modified "2023-10-06" @default.
• W2324881013 title "Oral Sucrose to Decrease Pain Associated With Arterial Puncture in Infants 30 to 36 Weeks' Gestation" @default.
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• W2324881013 doi "https://doi.org/10.1097/anc.0b013e318235c1ff" @default.
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