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- W2324881462 abstract "Introduction and aim: Cholangiocarcinoma (CCA), an aggressive liver malignancy with strong chemo-resistance, is surrounded by an abundant tumor reactive stroma, where cytokines regulating cell proliferation and survival are released. Their modulation may represent a potential therapeutic target. Among these cytokines, IL-6 is a potent growth factor for normal and neoplastic cholangiocytes. We sought to investigate the effects of leukaemia inhibitory factor (LIF), a member of the IL-6 family, that induces proliferation in several cancers, but has unknown effects in CCA." @default.
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- W2324881462 date "2014-02-01" @default.
- W2324881462 modified "2023-09-26" @default.
- W2324881462 title "Leukaemia inhibitory factor protects cholangiocarcinoma cells from cytotoxicity via a STAT-3-independent, Mcl-1 activation" @default.
- W2324881462 doi "https://doi.org/10.1016/j.dld.2014.01.145" @default.
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