Matches in SemOpenAlex for { <https://semopenalex.org/work/W2324889213> ?p ?o ?g. }
- W2324889213 endingPage "1776" @default.
- W2324889213 startingPage "1772" @default.
- W2324889213 abstract "Hydroxamic acids were designed, synthesized, and evaluated for their ability to selectively inhibit human histone deacetylase 6 (HDAC6). Several inhibitors, including compound 14 (BRD9757), exhibited excellent potency and selectivity despite the absence of a surface-binding motif. The binding of these highly efficient ligands for HDAC6 is rationalized via structure–activity relationships. These results demonstrate that high selectivity and potent inhibition of HDAC6 can be achieved through careful choice of linker element only." @default.
- W2324889213 created "2016-06-24" @default.
- W2324889213 creator A5010951409 @default.
- W2324889213 creator A5028971872 @default.
- W2324889213 creator A5030497146 @default.
- W2324889213 creator A5045123031 @default.
- W2324889213 creator A5045341176 @default.
- W2324889213 creator A5049183478 @default.
- W2324889213 creator A5051474045 @default.
- W2324889213 creator A5055094628 @default.
- W2324889213 creator A5068256561 @default.
- W2324889213 creator A5080133005 @default.
- W2324889213 creator A5082332788 @default.
- W2324889213 date "2013-02-18" @default.
- W2324889213 modified "2023-10-07" @default.
- W2324889213 title "Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif" @default.
- W2324889213 cites W1964951942 @default.
- W2324889213 cites W1967018540 @default.
- W2324889213 cites W1972299138 @default.
- W2324889213 cites W1976507388 @default.
- W2324889213 cites W1979832500 @default.
- W2324889213 cites W1980611668 @default.
- W2324889213 cites W1991647627 @default.
- W2324889213 cites W1995132116 @default.
- W2324889213 cites W1998585946 @default.
- W2324889213 cites W2008312146 @default.
- W2324889213 cites W2008525757 @default.
- W2324889213 cites W2012887006 @default.
- W2324889213 cites W2013434401 @default.
- W2324889213 cites W2014885180 @default.
- W2324889213 cites W2015047229 @default.
- W2324889213 cites W2024868635 @default.
- W2324889213 cites W2029148944 @default.
- W2324889213 cites W2029689327 @default.
- W2324889213 cites W2034859720 @default.
- W2324889213 cites W2052887007 @default.
- W2324889213 cites W2053368188 @default.
- W2324889213 cites W2055237164 @default.
- W2324889213 cites W2063078660 @default.
- W2324889213 cites W2064959533 @default.
- W2324889213 cites W2073978750 @default.
- W2324889213 cites W2077293502 @default.
- W2324889213 cites W2077715783 @default.
- W2324889213 cites W2079720515 @default.
- W2324889213 cites W2087961967 @default.
- W2324889213 cites W2088131137 @default.
- W2324889213 cites W2090760765 @default.
- W2324889213 cites W2095026025 @default.
- W2324889213 cites W2099118364 @default.
- W2324889213 cites W2099803844 @default.
- W2324889213 cites W2101127235 @default.
- W2324889213 cites W2107733280 @default.
- W2324889213 cites W2108017291 @default.
- W2324889213 cites W2124258829 @default.
- W2324889213 cites W2127073449 @default.
- W2324889213 cites W2128151020 @default.
- W2324889213 cites W2134682046 @default.
- W2324889213 cites W2137147094 @default.
- W2324889213 cites W2142278633 @default.
- W2324889213 cites W4211075966 @default.
- W2324889213 doi "https://doi.org/10.1021/jm301355j" @default.
- W2324889213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23368884" @default.
- W2324889213 hasPublicationYear "2013" @default.
- W2324889213 type Work @default.
- W2324889213 sameAs 2324889213 @default.
- W2324889213 citedByCount "100" @default.
- W2324889213 countsByYear W23248892132013 @default.
- W2324889213 countsByYear W23248892132014 @default.
- W2324889213 countsByYear W23248892132015 @default.
- W2324889213 countsByYear W23248892132016 @default.
- W2324889213 countsByYear W23248892132017 @default.
- W2324889213 countsByYear W23248892132018 @default.
- W2324889213 countsByYear W23248892132019 @default.
- W2324889213 countsByYear W23248892132020 @default.
- W2324889213 countsByYear W23248892132021 @default.
- W2324889213 countsByYear W23248892132022 @default.
- W2324889213 countsByYear W23248892132023 @default.
- W2324889213 crossrefType "journal-article" @default.
- W2324889213 hasAuthorship W2324889213A5010951409 @default.
- W2324889213 hasAuthorship W2324889213A5028971872 @default.
- W2324889213 hasAuthorship W2324889213A5030497146 @default.
- W2324889213 hasAuthorship W2324889213A5045123031 @default.
- W2324889213 hasAuthorship W2324889213A5045341176 @default.
- W2324889213 hasAuthorship W2324889213A5049183478 @default.
- W2324889213 hasAuthorship W2324889213A5051474045 @default.
- W2324889213 hasAuthorship W2324889213A5055094628 @default.
- W2324889213 hasAuthorship W2324889213A5068256561 @default.
- W2324889213 hasAuthorship W2324889213A5080133005 @default.
- W2324889213 hasAuthorship W2324889213A5082332788 @default.
- W2324889213 hasConcept C104317684 @default.
- W2324889213 hasConcept C111919701 @default.
- W2324889213 hasConcept C118792377 @default.
- W2324889213 hasConcept C161790260 @default.
- W2324889213 hasConcept C185592680 @default.
- W2324889213 hasConcept C23681527 @default.
- W2324889213 hasConcept C2776281265 @default.
- W2324889213 hasConcept C2778305200 @default.
- W2324889213 hasConcept C2780557392 @default.