FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W232513231> ?p ?o ?g. }

• W232513231 abstract "approved: ^ ,. , >- fti. Suk Y. 6h w* Normal human skin fibroblast cells were used to study the effect of zinc supplementation of the media on cell growth and the competitive binding activity of low density lipoprotein (LDL). Cells were grown in the media containing Dulbecco's Modified-Eagle Medium (DMEM), 5% (v/v) fetal calf serum (FCS), and various levels of zinc. Cell counts and protein determination revealed that there was no stimulatory effect of zinc on the growth of cells, showing a flat growth curve with up to 6 (ig/ml zinc supplementation. However, zinc supplementation of greater than 6 |_Lg/ml to the medium appeared to be toxic to the cell and thereby prevented growth. When zinc was removed from the medium using Epoxy-activated Sepharose 6B coupled with iminodiacetate, zinc concentration in the medium was markedly reduced to 0.045 jj.g/ml from 0.210 (ig/ml. The cell growth study using this zinc depleted medium exhibited a growth curve similar to that obtained from the earlier study, suggesting that 0.045 jig/ml of zinc in the control medium was still sufficient to support normal cell growth. For the LDL binding study, cells were grown in the media with various levels of zinc supplementation for 7 days and the competitive binding activity of LDL was determined. When cells were grown in the zinc removed medium with 1.5 (j.g/ml zinc supplementation, the maximum amounts 125 of I-LDL bound and internalized in the cells were observed; however, higher levels of zinc supplementation to the growth medium 125 caused decreased I-LDL binding to the cell receptors. These results suggest that zinc may be involved in the binding of LDL to" @default.
• W232513231 created "2016-06-24" @default.
• W232513231 creator A5042628913 @default.
• W232513231 date "1983-04-27" @default.
• W232513231 modified "2023-09-27" @default.
• W232513231 title "Effect of zinc supplementation on cell growth and lipoprotein binding in human fibroblast cells" @default.
• W232513231 cites W1511213324 @default.
• W232513231 cites W1532896263 @default.
• W232513231 cites W1549397399 @default.
• W232513231 cites W1581288183 @default.
• W232513231 cites W1588205173 @default.
• W232513231 cites W1775749144 @default.
• W232513231 cites W1979804517 @default.
• W232513231 cites W1981704568 @default.
• W232513231 cites W1986316392 @default.
• W232513231 cites W1992589107 @default.
• W232513231 cites W1994886424 @default.
• W232513231 cites W2004410658 @default.
• W232513231 cites W2020163158 @default.
• W232513231 cites W2021537613 @default.
• W232513231 cites W2022758175 @default.
• W232513231 cites W2034373809 @default.
• W232513231 cites W2047922146 @default.
• W232513231 cites W2055026787 @default.
• W232513231 cites W2076907924 @default.
• W232513231 cites W2079110550 @default.
• W232513231 cites W2091015159 @default.
• W232513231 cites W2100075764 @default.
• W232513231 cites W2112233943 @default.
• W232513231 cites W2113981144 @default.
• W232513231 cites W2130877202 @default.
• W232513231 cites W2135503869 @default.
• W232513231 cites W2163066705 @default.
• W232513231 cites W2235046188 @default.
• W232513231 cites W2257816160 @default.
• W232513231 cites W2290152386 @default.
• W232513231 cites W2336559915 @default.
• W232513231 cites W2341278415 @default.
• W232513231 cites W2472128031 @default.
• W232513231 cites W3148478643 @default.
• W232513231 cites W86474392 @default.
• W232513231 hasPublicationYear "1983" @default.
• W232513231 type Work @default.
• W232513231 sameAs 232513231 @default.
• W232513231 citedByCount "0" @default.
• W232513231 crossrefType "dissertation" @default.
• W232513231 hasAuthorship W232513231A5042628913 @default.
• W232513231 hasConcept C126322002 @default.
• W232513231 hasConcept C134018914 @default.
• W232513231 hasConcept C1491633281 @default.
• W232513231 hasConcept C153911025 @default.
• W232513231 hasConcept C16685009 @default.
• W232513231 hasConcept C178790620 @default.
• W232513231 hasConcept C185592680 @default.
• W232513231 hasConcept C202751555 @default.
• W232513231 hasConcept C2780381497 @default.
• W232513231 hasConcept C535196362 @default.
• W232513231 hasConcept C54355233 @default.
• W232513231 hasConcept C55493867 @default.
• W232513231 hasConcept C62112901 @default.
• W232513231 hasConcept C71924100 @default.
• W232513231 hasConcept C81885089 @default.
• W232513231 hasConcept C86803240 @default.
• W232513231 hasConceptScore W232513231C126322002 @default.
• W232513231 hasConceptScore W232513231C134018914 @default.
• W232513231 hasConceptScore W232513231C1491633281 @default.
• W232513231 hasConceptScore W232513231C153911025 @default.
• W232513231 hasConceptScore W232513231C16685009 @default.
• W232513231 hasConceptScore W232513231C178790620 @default.
• W232513231 hasConceptScore W232513231C185592680 @default.
• W232513231 hasConceptScore W232513231C202751555 @default.
• W232513231 hasConceptScore W232513231C2780381497 @default.
• W232513231 hasConceptScore W232513231C535196362 @default.
• W232513231 hasConceptScore W232513231C54355233 @default.
• W232513231 hasConceptScore W232513231C55493867 @default.
• W232513231 hasConceptScore W232513231C62112901 @default.
• W232513231 hasConceptScore W232513231C71924100 @default.
• W232513231 hasConceptScore W232513231C81885089 @default.
• W232513231 hasConceptScore W232513231C86803240 @default.
• W232513231 hasLocation W2325132311 @default.
• W232513231 hasOpenAccess W232513231 @default.
• W232513231 hasPrimaryLocation W2325132311 @default.
• W232513231 hasRelatedWork W1018987764 @default.
• W232513231 hasRelatedWork W1969154602 @default.
• W232513231 hasRelatedWork W1976790565 @default.
• W232513231 hasRelatedWork W1979579950 @default.
• W232513231 hasRelatedWork W1984344088 @default.
• W232513231 hasRelatedWork W2019762928 @default.
• W232513231 hasRelatedWork W2031766885 @default.
• W232513231 hasRelatedWork W2033458917 @default.
• W232513231 hasRelatedWork W2043271815 @default.
• W232513231 hasRelatedWork W2052795559 @default.
• W232513231 hasRelatedWork W2065958014 @default.
• W232513231 hasRelatedWork W2083094460 @default.
• W232513231 hasRelatedWork W2089465640 @default.
• W232513231 hasRelatedWork W2093486209 @default.
• W232513231 hasRelatedWork W2105867749 @default.
• W232513231 hasRelatedWork W2124411815 @default.
• W232513231 hasRelatedWork W2142017330 @default.
• W232513231 hasRelatedWork W2405448527 @default.

• next