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- W2325301216 abstract "The observations of Blotner and Murphy1, 2 seemed to indicate that certain aqueous liver extracts, as well as liver itself, contain a substance which, when given by mouth, reduces the insulin requirement of diabetic patients. More recently, de Pencier, Soskin and Best3 stated that the findings of Blotner and Murphy were not substantiated by observations on depancreatized dogs. In all of the work done by both of the above groups, calves' liver was used. The fact that chickens and ducks do not develop a typical Von Mering-Minkowski diabetes 4-8 suggested that chicken liver be tried instead of calves' liver. At the same time it seemed to be desirable to repeat the work of de Pencier, Soskin and Best.Two dogs were totally depancreatized. Two accurately weighed meals were fed each day, the hour being constant at all times. Urine was collected at exactly the same time every day, and quantitative sugar determinations were made by the Benedict method. Minced calf-pancreas was added to the diet. Insulin was given ..." @default.
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- W2325301216 date "1935-04-01" @default.
- W2325301216 modified "2023-09-26" @default.
- W2325301216 title "Influence of Chicken Liver Feeding on Depancreatized Dogs" @default.
- W2325301216 doi "https://doi.org/10.3181/00379727-32-8033c" @default.
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