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• W2325637054 abstract "The ruby laser shots cause selectively damages of the cutaneous melanin granules, but the cutaneous histological changes after the irradiation has not been well described. We applied the ruby laser to an excised skin using TOSHIBA Model LRT-301A. In this study, histological examinations were carried out light and electron microscopically. The results revealed as follows; 9J/cm2: Vacuolated changes were seen on the cells with melanin pigment in the basal layer. 16J/cm2: The vacuolation of cells among the basal cells was observed as elongated and degenerated In shape. The ring-like degeneration showing a crater was seen with incontinentia pigmenti histologica in dermal papilla. 25J/cm2: Diffuse degenerations were seen in the basal layer. Excoriation were most frequently seen at this energy radiated skin. 40J/cm2: Diffuse degenerations were also observed in the epidermis and dermal papilla with subepidermal cleft.The study demonstrated that in the efficacy of the ruby laser therapy to the dermal pigment disorders, the high energy irradiation was not always necessary, because over energy-irradiation was absorbed by epidermal melanin granules (epidermal trap) and the basement membrane was also damaged." @default.
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• W2325637054 date "1990-01-01" @default.
• W2325637054 modified "2023-09-25" @default.
• W2325637054 title "Histological studies on Human Skin after Irradiation of Ruby Laser" @default.
• W2325637054 doi "https://doi.org/10.2530/jslsm1980.11.supplement_581" @default.
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