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• W2325704191 abstract "Triazole prophylaxis has become the norm in patients with hematological malignancies. Breakthrough infections caused by Mucorales during triazole prophylaxis remain a challenging problem. We found that preexposure of Rhizopus oryzae to antifungal triazoles (fluconazole, voriconazole, posaconazole, and itraconazole) did not modify the in vitro susceptibility of Rhizopus oryzae to posaconazole. In contrast, preexposure of Rhizopus to triazoles was associated with the enhanced in vitro susceptibility of R. oryzae to amphotericin B. Preexposure to posaconazole did not alter the virulence of R. oryzae in the fly model of mucormycosis." @default.
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• W2325704191 date "2015-12-01" @default.
• W2325704191 modified "2023-10-05" @default.
• W2325704191 title "Effect of Preexposure to Triazoles on Susceptibility and Virulence of Rhizopus oryzae" @default.
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• W2325704191 doi "https://doi.org/10.1128/aac.01583-15" @default.
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