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- W2325713634 abstract "Sir: We reviewed with great interest the article by Stump et al. comparing capsule formation around breast implants in the presence and absence of AlloDerm (LifeCell Corp., Branchburg, N.J.) in primates and concluding that the use of AlloDerm effectively prevents capsule formation.1 We wish to bring to your attention several components of the article that have the potential to undermine the strength of this argument. In the middle of the article, there is a deviation in the p value used for significance from 0.05, the originally designated threshold in the Materials and Methods section, to 0.01. This newly set, tighter p value allows the authors to dismiss the difference between their control and experimental specimens in myofibroblast staining intensity at the deep layers, where AlloDerm did not cover the implant, as insignificant even though the reported p value for this was 0.0381, while still claiming statistical significance in the differences at the anterior and lateral periimplant tissues, where AlloDerm made contact in the experimental specimens. Clarification of this change in p value is warranted so that the results may be correctly evaluated. Furthermore, the two photographs used in their Figure 6 to depict the intense myofibroblast staining of the deep periimplant tissues of both control and experimental specimens appear alarmingly identical based on the histologic architecture seen. If in fact the two photographs published are the same, we assume this was simply an unintentional error, and submit that the original article would be enhanced if an erratum is published with the correct set of photographs. Nicholas Kim, B.S. Jonathan D. McCue, M.D. Bruce L. Cunningham, M.D., M.S. Division of Plastic and Reconstructive Surgery University of Minnesota Minneapolis, Minn." @default.
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- W2325713634 date "2010-11-01" @default.
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- W2325713634 title "A Commentary on Acellular Dermal Matrix in Preventing Capsule Formation around Implants in a Primate Model" @default.
- W2325713634 cites W2087949374 @default.
- W2325713634 doi "https://doi.org/10.1097/prs.0b013e3181ef9261" @default.
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