FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2325893453> ?p ?o ?g. }

• W2325893453 endingPage "138" @default.
• W2325893453 startingPage "131" @default.
• W2325893453 abstract "Background We have previously demonstrated that tolerance to a vascularized composite allograft (VCA) can be achieved after the establishment of mixed chimerism. We test the hypothesis that tolerance to a VCA in our dog leukocyte antigen–matched canine model is not dependent on the previous establishment of mixed chimerism and can be induced coincident with hematopoietic cell transplantation (HCT). Methods Eight dog leukocyte antigen–matched, minor antigen mismatched dogs received 200 cGy of radiation and a VCA transplant. Four dogs received donor bone marrow at the time of VCA transplantation (group 1), whereas a second group of four dogs did not (group 2). All recipients received a limited course of postgrafting immunosuppression. All dogs that received HCT and VCA were given donor, third-party, and autologous skin grafts. Results All group 1 recipients were tolerant to their VCA (>62 weeks). Three of the four dogs in group 2 rejected their VCA transplants after the cessation of immunosuppression. Biopsies obtained from the muscle and skin of VCA from group 1 showed few infiltrating cells compared with extensive infiltrates in biopsies of VCA from group 2. Compared with autologous skin and muscle, elevated levels of CD3+ FoxP3+ T-regulatory cells were found in the skin and muscle obtained from the VCA of HCT recipients. All group 1 animals were tolerant to their donor skin graft and promptly rejected the third-party skin grafts. Conclusion These data demonstrated that donor-specific tolerance to all components of the VCA can be established through simultaneous nonmyeloablative allogeneic HCT and VCA transplantation protocol." @default.
• W2325893453 created "2016-06-24" @default.
• W2325893453 creator A5008562447 @default.
• W2325893453 creator A5022960930 @default.
• W2325893453 creator A5053247976 @default.
• W2325893453 creator A5055138845 @default.
• W2325893453 creator A5062597461 @default.
• W2325893453 creator A5070467855 @default.
• W2325893453 creator A5072472626 @default.
• W2325893453 creator A5085787488 @default.
• W2325893453 date "2014-07-27" @default.
• W2325893453 modified "2023-10-15" @default.
• W2325893453 title "Simultaneous Transplantation of Hematopoietic Stem Cells and a Vascularized Composite Allograft Leads to Tolerance" @default.
• W2325893453 cites W1599241152 @default.
• W2325893453 cites W1975294422 @default.
• W2325893453 cites W1976955364 @default.
• W2325893453 cites W1979594892 @default.
• W2325893453 cites W1980864739 @default.
• W2325893453 cites W1983311716 @default.
• W2325893453 cites W1983329640 @default.
• W2325893453 cites W1999348754 @default.
• W2325893453 cites W2000432729 @default.
• W2325893453 cites W2001079563 @default.
• W2325893453 cites W2008147795 @default.
• W2325893453 cites W2014991983 @default.
• W2325893453 cites W2036939652 @default.
• W2325893453 cites W2040410917 @default.
• W2325893453 cites W2043553401 @default.
• W2325893453 cites W2043862280 @default.
• W2325893453 cites W2052271935 @default.
• W2325893453 cites W2058548801 @default.
• W2325893453 cites W2060147676 @default.
• W2325893453 cites W2067089684 @default.
• W2325893453 cites W2069397360 @default.
• W2325893453 cites W2077319771 @default.
• W2325893453 cites W2085151036 @default.
• W2325893453 cites W2111329034 @default.
• W2325893453 cites W2172047734 @default.
• W2325893453 cites W2314260375 @default.
• W2325893453 cites W4239255095 @default.
• W2325893453 cites W4294349031 @default.
• W2325893453 doi "https://doi.org/10.1097/tp.0000000000000204" @default.
• W2325893453 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4128556" @default.
• W2325893453 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24918616" @default.
• W2325893453 hasPublicationYear "2014" @default.
• W2325893453 type Work @default.
• W2325893453 sameAs 2325893453 @default.
• W2325893453 citedByCount "32" @default.
• W2325893453 countsByYear W23258934532014 @default.
• W2325893453 countsByYear W23258934532015 @default.
• W2325893453 countsByYear W23258934532016 @default.
• W2325893453 countsByYear W23258934532017 @default.
• W2325893453 countsByYear W23258934532018 @default.
• W2325893453 countsByYear W23258934532020 @default.
• W2325893453 countsByYear W23258934532021 @default.
• W2325893453 countsByYear W23258934532022 @default.
• W2325893453 countsByYear W23258934532023 @default.
• W2325893453 crossrefType "journal-article" @default.
• W2325893453 hasAuthorship W2325893453A5008562447 @default.
• W2325893453 hasAuthorship W2325893453A5022960930 @default.
• W2325893453 hasAuthorship W2325893453A5053247976 @default.
• W2325893453 hasAuthorship W2325893453A5055138845 @default.
• W2325893453 hasAuthorship W2325893453A5062597461 @default.
• W2325893453 hasAuthorship W2325893453A5070467855 @default.
• W2325893453 hasAuthorship W2325893453A5072472626 @default.
• W2325893453 hasAuthorship W2325893453A5085787488 @default.
• W2325893453 hasBestOaLocation W23258934531 @default.
• W2325893453 hasConcept C109159458 @default.
• W2325893453 hasConcept C141071460 @default.
• W2325893453 hasConcept C142724271 @default.
• W2325893453 hasConcept C147483822 @default.
• W2325893453 hasConcept C203014093 @default.
• W2325893453 hasConcept C2777702733 @default.
• W2325893453 hasConcept C2779727006 @default.
• W2325893453 hasConcept C2780007613 @default.
• W2325893453 hasConcept C2780252810 @default.
• W2325893453 hasConcept C28328180 @default.
• W2325893453 hasConcept C2911091166 @default.
• W2325893453 hasConcept C54355233 @default.
• W2325893453 hasConcept C71924100 @default.
• W2325893453 hasConcept C86803240 @default.
• W2325893453 hasConcept C8891405 @default.
• W2325893453 hasConceptScore W2325893453C109159458 @default.
• W2325893453 hasConceptScore W2325893453C141071460 @default.
• W2325893453 hasConceptScore W2325893453C142724271 @default.
• W2325893453 hasConceptScore W2325893453C147483822 @default.
• W2325893453 hasConceptScore W2325893453C203014093 @default.
• W2325893453 hasConceptScore W2325893453C2777702733 @default.
• W2325893453 hasConceptScore W2325893453C2779727006 @default.
• W2325893453 hasConceptScore W2325893453C2780007613 @default.
• W2325893453 hasConceptScore W2325893453C2780252810 @default.
• W2325893453 hasConceptScore W2325893453C28328180 @default.
• W2325893453 hasConceptScore W2325893453C2911091166 @default.
• W2325893453 hasConceptScore W2325893453C54355233 @default.
• W2325893453 hasConceptScore W2325893453C71924100 @default.
• W2325893453 hasConceptScore W2325893453C86803240 @default.
• W2325893453 hasConceptScore W2325893453C8891405 @default.
• W2325893453 hasIssue "2" @default.

• next