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- W2325958082 abstract "In a previous paper we described an electrophoretic analysis of several antipneumococcal horse sera that showed antibody activity in the γ-component. Since then 2 of the horses have been used to produce tetanal antitoxin. Subsequent electrophoretic analyses detected the appearance of a new component apparently associated with the freshly developed antitoxic activity. Early in September, 1939, horses No. 9514 and No. 6225 began to receive tetanal toxin instead of Types 1 and 2 pneumococcal antigens. Three months later they had high antitoxin-titers. Electrophoretic analyses of sera taken then, and before immunization with toxin had begun, are reproduced in Figs. 1 to 4. Only traces of antipneumococcal precipitin could be found in the sera taken in December and areas underlying the γ-peaks had obviously decreased greatly. With the development of antitoxin there had appeared, however, a strong new component (labeled T) with a mobility, -2.2 × 10-5 cm sec-1 volts-1, midway between β and γ. The same component was present in the strongly antitoxic serum of horse No. 756, which had never been used before for antibody-production, and in the sera of other horses producing tetanal antitoxin." @default.
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- W2325958082 date "1940-02-01" @default.
- W2325958082 modified "2023-10-18" @default.
- W2325958082 title "An Electrophoretic Study of Tetanus Antitoxin Sera" @default.
- W2325958082 doi "https://doi.org/10.3181/00379727-43-11220p" @default.
- W2325958082 hasPublicationYear "1940" @default.
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