Matches in SemOpenAlex for { <https://semopenalex.org/work/W2326027285> ?p ?o ?g. }
- W2326027285 endingPage "7" @default.
- W2326027285 startingPage "1" @default.
- W2326027285 abstract "Drugs of abuse cause a variety of complex neuronal events at the cellular level, including changes in membrane excitability and neurotransmission, activation of complex signaling pathways, altered synaptic physiology and structural changes, and drug-evoked synaptic plasticity and neurotoxicity, which mediate both acuteand long-lasting effects and addiction. Neuronal mitochondria are highly dynamic organelles that, by undergoing fusion and fission events, are efficiently translocated along the neuronal processes, frequently changing direction, pausing or switching to persistent docking. The neuronal integrity and functionality are dependent upon the proper maintenance of a healthy mitochondrial population and their efficient distribution. There is a general consensus that mitochondrial-dependent pathways can provide a major understanding concerning pathological processes underlying neurotoxicity of drugs of abuse. As such, it is plausible to consider that alterations on mitochondrial trafficking may be key players on the neuronal effects mediated by these drugs. This work aims to provide a comprehensive and up-to-date review of the data linking mitochondrial trafficking impairment to amphetamine-like drugs, and, thus, contribute to a better understanding of their neuronal effects. Additionally, new research data describing alterations in neuronal mitochondrial trafficking for 3,4-methylenedioxymethamphetamine (MDMA; “ecstasy”) conjugated metabolites 5-(glutathion-S-yl)-N-methyl-α-methyldopamine [5-(GSH)-N-Me-α-MeDA] and 5-(N-acetylcystein-S-yl)-N-methyl-α- methyldopamine [5-(NAC)-N-Me-α-MeDA] are also provided." @default.
- W2326027285 created "2016-06-24" @default.
- W2326027285 creator A5005684789 @default.
- W2326027285 creator A5036696962 @default.
- W2326027285 creator A5044335769 @default.
- W2326027285 creator A5045991293 @default.
- W2326027285 creator A5050992777 @default.
- W2326027285 creator A5062341762 @default.
- W2326027285 creator A5083621146 @default.
- W2326027285 creator A5087896622 @default.
- W2326027285 date "2014-01-01" @default.
- W2326027285 modified "2023-10-18" @default.
- W2326027285 title "Neuronal Mitochondrial Trafficking Impairment: The Cause or a Consequence of Neuronal Dysfunction Caused by Amphetamine-Like Drugs" @default.
- W2326027285 cites W1537243389 @default.
- W2326027285 cites W1545569420 @default.
- W2326027285 cites W1553062339 @default.
- W2326027285 cites W1588319081 @default.
- W2326027285 cites W1967513977 @default.
- W2326027285 cites W1969148884 @default.
- W2326027285 cites W1970302092 @default.
- W2326027285 cites W1970716291 @default.
- W2326027285 cites W1971805318 @default.
- W2326027285 cites W1974750801 @default.
- W2326027285 cites W1981753633 @default.
- W2326027285 cites W1982988839 @default.
- W2326027285 cites W1985912952 @default.
- W2326027285 cites W1987845572 @default.
- W2326027285 cites W1989130535 @default.
- W2326027285 cites W1991700908 @default.
- W2326027285 cites W1992085755 @default.
- W2326027285 cites W1993696187 @default.
- W2326027285 cites W1996764498 @default.
- W2326027285 cites W1997563565 @default.
- W2326027285 cites W1998654006 @default.
- W2326027285 cites W2005732976 @default.
- W2326027285 cites W2019134223 @default.
- W2326027285 cites W2020059513 @default.
- W2326027285 cites W2024595059 @default.
- W2326027285 cites W2030602441 @default.
- W2326027285 cites W2030646074 @default.
- W2326027285 cites W2037091801 @default.
- W2326027285 cites W2040261381 @default.
- W2326027285 cites W2044227008 @default.
- W2326027285 cites W2045085957 @default.
- W2326027285 cites W2047460306 @default.
- W2326027285 cites W2048841731 @default.
- W2326027285 cites W2049016912 @default.
- W2326027285 cites W2052309340 @default.
- W2326027285 cites W2055572268 @default.
- W2326027285 cites W2060031105 @default.
- W2326027285 cites W2069280713 @default.
- W2326027285 cites W2071316675 @default.
- W2326027285 cites W2075421841 @default.
- W2326027285 cites W2085883101 @default.
- W2326027285 cites W2087961967 @default.
- W2326027285 cites W2090730172 @default.
- W2326027285 cites W2091286093 @default.
- W2326027285 cites W2094265661 @default.
- W2326027285 cites W2098024573 @default.
- W2326027285 cites W2098718365 @default.
- W2326027285 cites W2099890622 @default.
- W2326027285 cites W2103602171 @default.
- W2326027285 cites W2103607451 @default.
- W2326027285 cites W2112546324 @default.
- W2326027285 cites W2120001424 @default.
- W2326027285 cites W2128951033 @default.
- W2326027285 cites W2131454864 @default.
- W2326027285 cites W2131642921 @default.
- W2326027285 cites W2142084126 @default.
- W2326027285 cites W2144919948 @default.
- W2326027285 cites W2146760369 @default.
- W2326027285 cites W2148471604 @default.
- W2326027285 cites W2149090315 @default.
- W2326027285 cites W2151818435 @default.
- W2326027285 cites W2155643523 @default.
- W2326027285 cites W2168082049 @default.
- W2326027285 doi "https://doi.org/10.4303/jdar/235868" @default.
- W2326027285 hasPublicationYear "2014" @default.
- W2326027285 type Work @default.
- W2326027285 sameAs 2326027285 @default.
- W2326027285 citedByCount "1" @default.
- W2326027285 countsByYear W23260272852015 @default.
- W2326027285 crossrefType "journal-article" @default.
- W2326027285 hasAuthorship W2326027285A5005684789 @default.
- W2326027285 hasAuthorship W2326027285A5036696962 @default.
- W2326027285 hasAuthorship W2326027285A5044335769 @default.
- W2326027285 hasAuthorship W2326027285A5045991293 @default.
- W2326027285 hasAuthorship W2326027285A5050992777 @default.
- W2326027285 hasAuthorship W2326027285A5062341762 @default.
- W2326027285 hasAuthorship W2326027285A5083621146 @default.
- W2326027285 hasAuthorship W2326027285A5087896622 @default.
- W2326027285 hasConcept C169760540 @default.
- W2326027285 hasConcept C2777193897 @default.
- W2326027285 hasConcept C28859421 @default.
- W2326027285 hasConcept C513476851 @default.
- W2326027285 hasConcept C71924100 @default.
- W2326027285 hasConcept C86803240 @default.
- W2326027285 hasConcept C95444343 @default.