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- W2326105143 abstract "In Brief Published dosing schemes call for reduced dosage of polymyxin B for patients with renal insufficiency. However, recent evidence suggests that clearance of polymyxin B is not affected by renal function. We report a patient with renal insufficiency who had microbiological failure when adjusted dosing was administered but clearance of bacteremia when the dose was increased to that recommended for a patient with normal renal function. Even though polymyxins are being used more commonly with the emergence of resistant gram negative bacteria, appropriate dosing of Polymyxin B especially in patients with renal insufficiency remains unknown. This reported case indicates that dosage of polymyxin B adjusted for renal insufficiency may be inadequate." @default.
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- W2326105143 date "2013-03-01" @default.
- W2326105143 modified "2023-09-25" @default.
- W2326105143 title "Dose-Related Clinical Efficacy of Polymyxin B in a Critically Ill Patient" @default.
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- W2326105143 doi "https://doi.org/10.1097/ipc.0b013e318260221b" @default.
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