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- W2326306526 abstract "Giris ve amac: Mide malignitelerinde Helikobakter pilori s›kl›g›n›n tan›mlanmas› ve etiyolojideki degerinin saptanmas› amaclanm›st›r. Helikobakter pilori enfeksiyonu gastrik adenokarsinom ve gastrik lenfoma riskinde art›sla iliskilidir. Gerec ve yontem: 1998-2005 tarihleri aras›nda Ankara Egitim ve Arast›rma Hastanesi 2. ve 5. Genel Cerrahi Klinikleri’nde malignite nedeniyle total ve subtotal mide rezeksiyonu yap›lan 42 hastan›n gastrik spesimenleri retrospektif olarak tekrar incelendi. Histolojik degerlendirme Lauren’s klasifikasyonu ve Helikobakter pilori yogunluk tayini icin Sydney klasifikasyonu kullan›ld›. Bulgular: Cal›smaya 32 gastrik karsinoma, 10 non-Hodgkin gastrik lenfoma vakas› al›nd›. Helikobakter enfeksiyonu; gastrik karsinomlu hastalar›n 10’unda (%33.3), gastrik lenfomal› hastalar›n 7’sinde (%70) saptand›. Helikobakter yogunlugu 9 gastrik karsinomlu, 7 gastrik lenfomal› hastada ‘1’ iken, 1 gastrik karsinom vakas›nda ve 1 gastrik lenfomal› hastada yogunluk ‘2’ idi. Mide lenfomas› vakalar›nda Helikobakter pilori prevalans› anlaml› olarak daha yuksek idi. Helikobakter pilori, intestinal tip gastrik karsinoma nazaran difuz gastrik karsinomada daha s›k goruldu. Ayr›ca gastrik karsinom klinik evresi artt›kca Helikobakter pilori yogunlugu da artmakta birlikte istatistiksel olarak bu bulgular anlaml› bulunmad›. Sonuc: Gastrik maligniteler aras›nda lenfoma olgular›nda yuksek s›kl›kta Helikobakter pilori bulunmas› gastrik lenfoman›n olusmas›nda Helikobakter pilori’nin rolunu dogrulamaktad›r. Anahtar sozcukler: Helikobakter pilori, gastrik karsinoma, gastrik lenfoma Background/aim: We aimed to determine Helicobacter pylori prevalence in gastric malignant disease and to examine its value in the etiology. Infection with Helicobacter pylori is associated with an increased risk of gastric adenocarcinoma and gastric lymphoma. Materials and methods: We retrospectively examined the surgical specimens of 42 patients with malignant gastric tumors, who had been hospitalized in the second and fifth Department of General Surgery, Ministry of Health Ankara Training and Research Hospital, between 1998 and 2005 and treated with gastrectomy. Histological assessment and Helicobacter pylori density determinations were made according to Lauren and Sydney classifications, respectively. Results: Thirty-two had gastric carcinoma and 10 had gastric non-Hodgkin lymphoma. Helicobacter pylori infection was present in 10 (33.3%) of the gastric carcinoma patients and 7 (70%) of the gastric lymphoma patients. The density of Helicobacter pylori was ‘1’ in nine gastric carcinoma and six gastric lymphoma cases, and ‘2’ in one gastric carcinoma and one gastric lymphoma case. Helicobacter pylori prevalence is significantly higher in lymphoma cases than carcinoma cases. Diffuse type gastric carcinoma is more correlated with Helicobacter pylori than the intestinal type, and Helicobacter pylori density increases in conjunction with an increase in the gastric carcinoma clinical stage, but these findings were not significant. Conclusion: A high prevalence of Helicobacter pylori among the gastric lymphoma patients confirms the role of Helicobacter pylori in gastric lymphoma genesis." @default.
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- W2326306526 date "2006-01-01" @default.
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- W2326306526 title "Helicobacter pylori prevalance in gastric carcinoma and gastric lymphoma" @default.
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