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- W2326568545 abstract "Purpose The purposes of this study were to describe the imaging features and metastatic pattern of non–inferior vena cava (IVC) retroperitoneal leiomyosarcomas (non–IVC LMS) and to compare them with those of IVC leiomyosarcomas (IVC LMS) to assess any differences between the 2 groups. Materials and Methods In this institutional review board–approved, Health Insurance Portability and Accountability Act–compliant retrospective study, all 56 patients with pathologically confirmed primary retroperitoneal leiomyosarcoma (34 non–IVC LMS and 22 IVC LMS) seen at our tertiary cancer center during a 10-year period were included. All available imaging of primary tumor (18 non–IVC LMS and 19 IVC LMS) and follow-up imaging studies (on all 56 patients) were reviewed in consensus by 2 fellowship-trained oncoradiologists. Imaging features and metastatic spread of non–IVC LMS were described and compared with those of IVC LMS. Continuous variables were compared using the Student t test, binary variables with the Fisher exact test, and survival using the log-rank test. Results Non–inferior vena cava retroperitoneal leiomyosarcomas had a mean size of 11.3 cm (range, 3.7–27 cm) and most commonly occurred in the perirenal space (16/18). Primary tumors were hyperattenuating to muscle (11/18) and showed heterogeneous enhancement (17/18). Lungs (22/34), peritoneum (18/34), and liver (18/34) were the most common metastatic sites. There was no significant difference between the imaging features and metastatic pattern of non–IVC and IVC LMS. Although non–IVC LMS presented at a more advanced stage (P < 0.002), there was statistically non–significant trend toward better median survival of non–IVC LMS (P = 0.07). Conclusions Non–inferior vena cava retroperitoneal leiomyosarcomas are large heterogeneous tumors arising in the perirenal space and frequently metastasize to lungs, peritoneum, and liver. From a radiologist’s perspective, non–IVC LMS behave similar to IVC-LMS." @default.
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- W2326568545 date "2014-01-01" @default.
- W2326568545 modified "2023-10-14" @default.
- W2326568545 title "Imaging Features and Metastatic Pattern of Non–IVC Retroperitoneal Leiomyosarcomas" @default.
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- W2326568545 doi "https://doi.org/10.1097/rct.0000000000000097" @default.
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