FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2326885744> ?p ?o ?g. }

• W2326885744 endingPage "196" @default.
• W2326885744 startingPage "191" @default.
• W2326885744 abstract "Irritable bowel syndrome (IBS) is the most common functional bowel disorder and has a strong predominance in women. Recent data suggest that the brain may play an important role in the pathophysiology of IBS in the brain-gut axis. It is strongly suspected that serotonin (5-HT), a neurotransmitter found in the brain and gut, may be related to the pathophysiology of IBS. It is reported that a 5-HT3 antagonist is effective only in female patients with diarrhea-predominant IBS.In the present study, 5-HT synthesis was measured using positron emission tomography, with alpha-[11C]methyl-L-tryptophan as the tracer, in patients with IBS. The aim of the present study was to compare 5-HT synthesis in the IBS patients with that in the controls, and to compare 5-HT synthesis between male and female IBS patients.Six male and six female nonconstipated IBS patients were scanned. Age-matched healthy volunteers were scanned as controls. Eighty minute dynamic scans were performed. Functional 5-HT synthesis images were analyzed using statistical parametric mapping.5-HT synthesis was greater only in the female IBS patients in the right medial temporal gyrus (multimodal sensory association cortex) compared with the female controls (P<0.001).The greater brain 5-HT synthesis in the female IBS patients than in the controls may be related to the pathological visceral pain processing of the IBS patients, a larger female predominance of the disorder, and the sex difference of the efficacy of the 5-HT3 antagonist in treatment." @default.
• W2326885744 created "2016-06-24" @default.
• W2326885744 creator A5004693769 @default.
• W2326885744 creator A5007464229 @default.
• W2326885744 creator A5037002122 @default.
• W2326885744 creator A5042697408 @default.
• W2326885744 creator A5045006490 @default.
• W2326885744 creator A5053311329 @default.
• W2326885744 creator A5083969851 @default.
• W2326885744 date "2003-01-01" @default.
• W2326885744 modified "2023-10-13" @default.
• W2326885744 title "Sex Differences of Brain Serotonin Synthesis in Patients with Irritable Bowel Syndrome Using α-[¹¹C]methyl-L-tryptophan, Positron Emission Tomography and Statistical Parametric Mapping" @default.
• W2326885744 cites W1238819995 @default.
• W2326885744 cites W1431953741 @default.
• W2326885744 cites W1488352192 @default.
• W2326885744 cites W1606920119 @default.
• W2326885744 cites W1966123432 @default.
• W2326885744 cites W1966801160 @default.
• W2326885744 cites W1968187794 @default.
• W2326885744 cites W1979769335 @default.
• W2326885744 cites W1991271245 @default.
• W2326885744 cites W1993357824 @default.
• W2326885744 cites W2004463473 @default.
• W2326885744 cites W2008019573 @default.
• W2326885744 cites W2011658120 @default.
• W2326885744 cites W2035719855 @default.
• W2326885744 cites W2042737219 @default.
• W2326885744 cites W2043862537 @default.
• W2326885744 cites W2049489255 @default.
• W2326885744 cites W2051068515 @default.
• W2326885744 cites W2052451375 @default.
• W2326885744 cites W2059368872 @default.
• W2326885744 cites W2059804477 @default.
• W2326885744 cites W2060937339 @default.
• W2326885744 cites W2064644850 @default.
• W2326885744 cites W2065352110 @default.
• W2326885744 cites W2070888548 @default.
• W2326885744 cites W2089933763 @default.
• W2326885744 cites W2091075637 @default.
• W2326885744 cites W2092078486 @default.
• W2326885744 cites W2095024518 @default.
• W2326885744 cites W2102216249 @default.
• W2326885744 cites W2102579252 @default.
• W2326885744 cites W2107237727 @default.
• W2326885744 cites W2127837438 @default.
• W2326885744 cites W2136148445 @default.
• W2326885744 cites W2138579314 @default.
• W2326885744 cites W2154698044 @default.
• W2326885744 cites W2164470443 @default.
• W2326885744 cites W2169428430 @default.
• W2326885744 cites W2171267699 @default.
• W2326885744 cites W2619099808 @default.
• W2326885744 cites W3127623214 @default.
• W2326885744 cites W76740135 @default.
• W2326885744 doi "https://doi.org/10.1155/2003/572127" @default.
• W2326885744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12677270" @default.
• W2326885744 hasPublicationYear "2003" @default.
• W2326885744 type Work @default.
• W2326885744 sameAs 2326885744 @default.
• W2326885744 citedByCount "45" @default.
• W2326885744 countsByYear W23268857442012 @default.
• W2326885744 countsByYear W23268857442014 @default.
• W2326885744 countsByYear W23268857442015 @default.
• W2326885744 countsByYear W23268857442016 @default.
• W2326885744 countsByYear W23268857442018 @default.
• W2326885744 countsByYear W23268857442019 @default.
• W2326885744 countsByYear W23268857442020 @default.
• W2326885744 countsByYear W23268857442021 @default.
• W2326885744 countsByYear W23268857442022 @default.
• W2326885744 countsByYear W23268857442023 @default.
• W2326885744 crossrefType "journal-article" @default.
• W2326885744 hasAuthorship W2326885744A5004693769 @default.
• W2326885744 hasAuthorship W2326885744A5007464229 @default.
• W2326885744 hasAuthorship W2326885744A5037002122 @default.
• W2326885744 hasAuthorship W2326885744A5042697408 @default.
• W2326885744 hasAuthorship W2326885744A5045006490 @default.
• W2326885744 hasAuthorship W2326885744A5053311329 @default.
• W2326885744 hasAuthorship W2326885744A5083969851 @default.
• W2326885744 hasBestOaLocation W23268857441 @default.
• W2326885744 hasConcept C10162356 @default.
• W2326885744 hasConcept C126322002 @default.
• W2326885744 hasConcept C126838900 @default.
• W2326885744 hasConcept C134018914 @default.
• W2326885744 hasConcept C143409427 @default.
• W2326885744 hasConcept C15744967 @default.
• W2326885744 hasConcept C170493617 @default.
• W2326885744 hasConcept C207886595 @default.
• W2326885744 hasConcept C2775842073 @default.
• W2326885744 hasConcept C2775864247 @default.
• W2326885744 hasConcept C2778271842 @default.
• W2326885744 hasConcept C2989005 @default.
• W2326885744 hasConcept C39313694 @default.
• W2326885744 hasConcept C71924100 @default.
• W2326885744 hasConcept C90924648 @default.
• W2326885744 hasConceptScore W2326885744C10162356 @default.
• W2326885744 hasConceptScore W2326885744C126322002 @default.
• W2326885744 hasConceptScore W2326885744C126838900 @default.
• W2326885744 hasConceptScore W2326885744C134018914 @default.

• next