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- W2326958033 abstract "Human CEM cells were incubated with liposomes containing 15 mer oligodeoxyribonucleotide sequences. When the sequence was complementary to the 5'end of c-myc proto-oncogene mRNA, proliferation of the cells was blocked. Inhibition was not seen for empty lipsomes or lipsomes containing sequences irrelevant to c-myc mRNA. Nor was it seen when non-encapsulated oligonucleotides were incubated with cells, probably because non-encapsulated oligonucleotides are sensitive to nucleases. Oligodeoxyribonucleotides encapsulated in liposomes resists DNAse, and inhibit cell proliferation specifically." @default.
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- W2326958033 date "1995-01-01" @default.
- W2326958033 modified "2023-10-04" @default.
- W2326958033 title "Specific inhibition of DNA synthesis by liposomes containing c-myc antisense oligonucleotides." @default.
- W2326958033 doi "https://doi.org/10.2745/dds.10.193" @default.
- W2326958033 hasPublicationYear "1995" @default.
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