Matches in SemOpenAlex for { <https://semopenalex.org/work/W2326996801> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W2326996801 endingPage "162" @default.
- W2326996801 startingPage "160" @default.
- W2326996801 abstract "Polysaccharides derived from gravis, intermediate, and mitis types of C. diphtheriœ were found to be group-specific. Recent findings, however, indicate that any of these different cultural types may be present in a single serological type. Because of this an attempt was made to extend our previous study to include polysaccharides of different serological types of C. diphtheriœ with the object of determining the existence of type-specific polysaccharides. One organism from each of 5 distinct serological types kindly supplied to us by Sia and Huang was employed for the present study. All organisms, with the exception of Park 8 (Type D41) were isolated locally. The various characterizations of these organisms were as follows: All of the cultures were capable of eliciting precipitin antibodies in rabbits from 4 to 5 weeks when administered intravenously as heat-killed vaccines. The cultivation of organisms, the preparation of polysaccharides, and the immunization of rabbits were the same as those described previously. Absorption test was performed by mixing immune serum diluted 1:5 with well-washed living organisms grown on serum broth at 37°C for 48 hours and the mixture was incubated at 45°C waterbath for 2 hours. It was refrigerated overnight after which the serum was separated by rapid centrifugation. It was found that 2 kinds of polysaccharide could be demonstrated by the precipitin reaction and by absorption tests. These polysaccharides will be designated as A and B. Polysaccharide A was present in the types D25, D30, D41, and X. Identical precipitin titers varying from 1:50,000 to 1:100,000 were obtained when polysaccharides A were mixed in the ring test with the homologous as well as the heterologous immune sera prepared with the above types. Cross absorption tests performed by mixing immune serum with organisms belonging to any of the types D25, D30, D41, and X showed a removal of all precipitins without affecting the type-specific agglutinins." @default.
- W2326996801 created "2016-06-24" @default.
- W2326996801 creator A5046625428 @default.
- W2326996801 creator A5068238105 @default.
- W2326996801 date "1939-05-01" @default.
- W2326996801 modified "2023-10-14" @default.
- W2326996801 title "Type-Specific Polysaccharides of C. diphtheriae." @default.
- W2326996801 doi "https://doi.org/10.3181/00379727-41-10604p" @default.
- W2326996801 hasPublicationYear "1939" @default.
- W2326996801 type Work @default.
- W2326996801 sameAs 2326996801 @default.
- W2326996801 citedByCount "3" @default.
- W2326996801 crossrefType "journal-article" @default.
- W2326996801 hasAuthorship W2326996801A5046625428 @default.
- W2326996801 hasAuthorship W2326996801A5068238105 @default.
- W2326996801 hasConcept C100817775 @default.
- W2326996801 hasConcept C133229898 @default.
- W2326996801 hasConcept C159654299 @default.
- W2326996801 hasConcept C185592680 @default.
- W2326996801 hasConcept C203014093 @default.
- W2326996801 hasConcept C32611913 @default.
- W2326996801 hasConcept C45189115 @default.
- W2326996801 hasConcept C55493867 @default.
- W2326996801 hasConcept C7623868 @default.
- W2326996801 hasConcept C86803240 @default.
- W2326996801 hasConcept C89423630 @default.
- W2326996801 hasConceptScore W2326996801C100817775 @default.
- W2326996801 hasConceptScore W2326996801C133229898 @default.
- W2326996801 hasConceptScore W2326996801C159654299 @default.
- W2326996801 hasConceptScore W2326996801C185592680 @default.
- W2326996801 hasConceptScore W2326996801C203014093 @default.
- W2326996801 hasConceptScore W2326996801C32611913 @default.
- W2326996801 hasConceptScore W2326996801C45189115 @default.
- W2326996801 hasConceptScore W2326996801C55493867 @default.
- W2326996801 hasConceptScore W2326996801C7623868 @default.
- W2326996801 hasConceptScore W2326996801C86803240 @default.
- W2326996801 hasConceptScore W2326996801C89423630 @default.
- W2326996801 hasIssue "1" @default.
- W2326996801 hasLocation W23269968011 @default.
- W2326996801 hasOpenAccess W2326996801 @default.
- W2326996801 hasPrimaryLocation W23269968011 @default.
- W2326996801 hasRelatedWork W1496685087 @default.
- W2326996801 hasRelatedWork W1944313341 @default.
- W2326996801 hasRelatedWork W2029098033 @default.
- W2326996801 hasRelatedWork W2301722730 @default.
- W2326996801 hasRelatedWork W2316497470 @default.
- W2326996801 hasRelatedWork W2412516899 @default.
- W2326996801 hasRelatedWork W2605733738 @default.
- W2326996801 hasRelatedWork W4226328707 @default.
- W2326996801 hasRelatedWork W115830369 @default.
- W2326996801 hasRelatedWork W2345197927 @default.
- W2326996801 hasVolume "41" @default.
- W2326996801 isParatext "false" @default.
- W2326996801 isRetracted "false" @default.
- W2326996801 magId "2326996801" @default.
- W2326996801 workType "article" @default.