FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2327007162> ?p ?o ?g. }

• W2327007162 endingPage "608" @default.
• W2327007162 startingPage "602" @default.
• W2327007162 abstract "Objectives: Pediatric pancreatitis remains poorly understood despite increasing incidence and risk of morbidity and mortality. Present predictive scores for severe pediatric acute pancreatitis (AP) are either extrapolated from adults or difficult to use in practice. We aimed to identify laboratory parameters for early prediction of severity of the course of pediatric AP. Methods: A retrospective review of children with AP (January 2000–July 2011) was performed at 2 pediatric hospitals. Predictors of severe AP using laboratory parameters measured within 24 hours of presentation were derived in the cohort from one institution and validated in the other. Results: A total of 131 pancreatitis episodes, 73 (34% severe) and 58 (24% severe) in the derivation and validation cohorts respectively, were reviewed. In the derivation cohort, serum lipase was significantly higher in severe versus mild AP (median [interquartile range] 18.1 [9.2–39.1] vs 4.9 (3.2–13.3) × upper limit of normal [ULN]; P = 0.002). Logistic regression analysis in the derivation cohort showed serum lipase ≥7 × ULN to be predictive of severe AP. This finding was confirmed in the validation cohort. Based on the combined derivation and validation data, serum lipase ≥7 × ULN was associated with an odds ratio of 7.1 (95% confidence interval 2.5–20.5; P < 0.001) for developing severe AP. Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios were 85%, 56%, 46%, 89%, 1.939, and 0.27, respectively. Conclusions: Serum lipase ≥7 × ULN within 24 hours of presentation may be a simple clinical predictor of severe AP in children. Lipase levels below this threshold are strongly associated with a milder course." @default.
• W2327007162 created "2016-06-24" @default.
• W2327007162 creator A5063369263 @default.
• W2327007162 creator A5076332125 @default.
• W2327007162 creator A5088927649 @default.
• W2327007162 date "2013-06-01" @default.
• W2327007162 modified "2023-10-15" @default.
• W2327007162 title "Serum Lipase as an Early Predictor of Severity in Pediatric Acute Pancreatitis" @default.
• W2327007162 cites W1982227777 @default.
• W2327007162 cites W1984643078 @default.
• W2327007162 cites W1985045980 @default.
• W2327007162 cites W2011460762 @default.
• W2327007162 cites W2020069799 @default.
• W2327007162 cites W2034281304 @default.
• W2327007162 cites W2035725887 @default.
• W2327007162 cites W2037763787 @default.
• W2327007162 cites W2040198402 @default.
• W2327007162 cites W2041587252 @default.
• W2327007162 cites W2044739067 @default.
• W2327007162 cites W2049136850 @default.
• W2327007162 cites W2070616260 @default.
• W2327007162 cites W2080030512 @default.
• W2327007162 cites W2084204348 @default.
• W2327007162 cites W2084282801 @default.
• W2327007162 cites W2088817786 @default.
• W2327007162 cites W2097583060 @default.
• W2327007162 cites W2119630217 @default.
• W2327007162 cites W2127379250 @default.
• W2327007162 cites W2136196992 @default.
• W2327007162 cites W2171232047 @default.
• W2327007162 cites W2171290005 @default.
• W2327007162 cites W3210465440 @default.
• W2327007162 cites W4293242440 @default.
• W2327007162 doi "https://doi.org/10.1097/mpg.0b013e31828b36d8" @default.
• W2327007162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23403441" @default.
• W2327007162 hasPublicationYear "2013" @default.
• W2327007162 type Work @default.
• W2327007162 sameAs 2327007162 @default.
• W2327007162 citedByCount "69" @default.
• W2327007162 countsByYear W23270071622013 @default.
• W2327007162 countsByYear W23270071622014 @default.
• W2327007162 countsByYear W23270071622015 @default.
• W2327007162 countsByYear W23270071622016 @default.
• W2327007162 countsByYear W23270071622017 @default.
• W2327007162 countsByYear W23270071622018 @default.
• W2327007162 countsByYear W23270071622019 @default.
• W2327007162 countsByYear W23270071622020 @default.
• W2327007162 countsByYear W23270071622021 @default.
• W2327007162 countsByYear W23270071622022 @default.
• W2327007162 countsByYear W23270071622023 @default.
• W2327007162 crossrefType "journal-article" @default.
• W2327007162 hasAuthorship W2327007162A5063369263 @default.
• W2327007162 hasAuthorship W2327007162A5076332125 @default.
• W2327007162 hasAuthorship W2327007162A5088927649 @default.
• W2327007162 hasBestOaLocation W23270071621 @default.
• W2327007162 hasConcept C119060515 @default.
• W2327007162 hasConcept C120665830 @default.
• W2327007162 hasConcept C121332964 @default.
• W2327007162 hasConcept C126322002 @default.
• W2327007162 hasConcept C151956035 @default.
• W2327007162 hasConcept C156957248 @default.
• W2327007162 hasConcept C167135981 @default.
• W2327007162 hasConcept C198433322 @default.
• W2327007162 hasConcept C201903717 @default.
• W2327007162 hasConcept C2775967933 @default.
• W2327007162 hasConcept C2776670229 @default.
• W2327007162 hasConcept C30036603 @default.
• W2327007162 hasConcept C44249647 @default.
• W2327007162 hasConcept C61511704 @default.
• W2327007162 hasConcept C71924100 @default.
• W2327007162 hasConcept C72563966 @default.
• W2327007162 hasConcept C90924648 @default.
• W2327007162 hasConceptScore W2327007162C119060515 @default.
• W2327007162 hasConceptScore W2327007162C120665830 @default.
• W2327007162 hasConceptScore W2327007162C121332964 @default.
• W2327007162 hasConceptScore W2327007162C126322002 @default.
• W2327007162 hasConceptScore W2327007162C151956035 @default.
• W2327007162 hasConceptScore W2327007162C156957248 @default.
• W2327007162 hasConceptScore W2327007162C167135981 @default.
• W2327007162 hasConceptScore W2327007162C198433322 @default.
• W2327007162 hasConceptScore W2327007162C201903717 @default.
• W2327007162 hasConceptScore W2327007162C2775967933 @default.
• W2327007162 hasConceptScore W2327007162C2776670229 @default.
• W2327007162 hasConceptScore W2327007162C30036603 @default.
• W2327007162 hasConceptScore W2327007162C44249647 @default.
• W2327007162 hasConceptScore W2327007162C61511704 @default.
• W2327007162 hasConceptScore W2327007162C71924100 @default.
• W2327007162 hasConceptScore W2327007162C72563966 @default.
• W2327007162 hasConceptScore W2327007162C90924648 @default.
• W2327007162 hasIssue "6" @default.
• W2327007162 hasLocation W23270071621 @default.
• W2327007162 hasLocation W23270071622 @default.
• W2327007162 hasLocation W23270071623 @default.
• W2327007162 hasOpenAccess W2327007162 @default.
• W2327007162 hasPrimaryLocation W23270071621 @default.
• W2327007162 hasRelatedWork W1262047160 @default.
• W2327007162 hasRelatedWork W2127212281 @default.
• W2327007162 hasRelatedWork W2154098440 @default.

• next