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- W2327092504 abstract "To report the safety and efficacy of percutaneous image-guided cryoablation of soft tissue venous vascular malformations. HIPAA approved mono-institutional retrospective study of 26 patients presenting venous vascular malformation in soft tissue and treated with cryoablation for symptomatic recurrences after sclerosis (N=16) or in case of non-indication of sclerosis (N=9). Eligibility criteria included initial radiological diagnosis of venous or glomovenous vascular malformation proved by Doppler ultrasound and MRI and follow-up of at least 6 months. The safety was evaluated according to the classification of the toxicity scale NCI-CTCAE and the quality of life by EORTC QLQ-C30 questionnaire. The number and proportion of success of cryoablation at 6 months was described on clinical evaluation performed at 7 days, 1 and 6 months and with MRI at 6 months according to RECIST 1.1. Patients’ ages ranged from 13 to 64 years (mean: 31,7). 6 were male and 20 female. Procedures were performed under local (N=3) and general (N=23) anesthesia. A technical success was observed in all cases using 2 cryoprobes in all cases. Only one severe adverse effect related to cryoablation occurred. Pain decreased significantly from 4 in mean (range 0 -10) before treatment to 2 (range 0-5) after 1 month (P<0.05) and 1.4 (range 0-6) after 6 months (P<0.05). After a transitory swelling (<15 days) occurring in all cases, a complete response was observed with a significant decrease of the mean volume from 12.5 cm3 (range: 1.1-62.3) to 4.3 cm3 (range: 0-53.5) at 6 months (P <0.05). Percutaneous cryoablation appears safe and effective to treat venous vascular malformation even in case of multiple previous treatments." @default.
- W2327092504 created "2016-06-24" @default.
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- W2327092504 date "2016-03-01" @default.
- W2327092504 modified "2023-10-05" @default.
- W2327092504 title "▪ FEATURED ABSTRACT Percutaneous image-guided cryoablation of soft-tissue venous vascular malformations: a study of safety and efficacy" @default.
- W2327092504 doi "https://doi.org/10.1016/j.jvir.2015.12.352" @default.
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