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- W2327100791 abstract "The complexity of multiple sclerosis (MS) and the incompetence of a large number of promised treatments for MS urge us to plan new and more effective therapeutic approaches that aim to suppress ongoing autoimmune responses and induction of local endogenous regeneration. Emerging data propose that hematopoietic, mesenchymal, and neural stem cells have the potential to restore self-tolerance, provide <i>in situ</i> immunomodulation and neuroprotection, as well as promote regeneration. Thus, in this article, we will first provide an overview of the cell sources for proposed mechanisms that contribute to the beneficial effects of stem cell transplantation, the ideal route and/or timing of stem cell-based therapies for each main stem cell group, and finally, an overview of the current status of stem cell research in clinical trial stages in MS by comparable and healthy therapeutic effects of different stem cell therapies for MS patients." @default.
- W2327100791 created "2016-06-24" @default.
- W2327100791 creator A5028056356 @default.
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- W2327100791 date "2016-01-01" @default.
- W2327100791 modified "2023-10-16" @default.
- W2327100791 title "The role of stem cell therapy in multiple sclerosis: An overview of the current status of the clinical studies" @default.
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- W2327100791 doi "https://doi.org/10.4103/2277-9175.178791" @default.
- W2327100791 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4817403" @default.
- W2327100791 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27110543" @default.
- W2327100791 hasPublicationYear "2016" @default.
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