Matches in SemOpenAlex for { <https://semopenalex.org/work/W2327484480> ?p ?o ?g. }
- W2327484480 endingPage "87" @default.
- W2327484480 startingPage "71" @default.
- W2327484480 abstract "Abstract A quantitative high yield method utilizing isosmotic arabino-galactan (Stractan) solutions and isopycnic centrifugation was developed to isolate and to fractionate total human platelet populations into density-dependent subpopulations. Isolated platelets were free of factor VIII/von Willebrand factor and other plasma proteins. They responded to ADP, epinephrine, and collagen with a sensitivity equal to platelet-rich plasma platelets. The correlation of platelet density with volume and ultrastructure was examined for normal subjects. Recovery of total platelet populations averaged 92.76%+/-3.64% (SD). Normal individuals exhibited a narrow range of platelet buoyant density distribution. Computerized probability plot analysis of platelet volume distribution for 15 normal subjects' total platelet populations showed a mean volume of 5.17+/-0.46 cu mum (SD). Platelets with buoyant density less than or equal to 1.062 g/ml had a mean volume of 4.50+/- 0.48 cu mum, while platelets with buoyant density greater than 1.071 g/ml, but less than or equal to 1.084 g/ml, had a mean volume of 5.32+/- 0.63 cu mum (SD). The volume difference by paired t test was significant, p less than 0.001. Thin-section electron microscopy demonstrated a significant reduction of granule content in light platelets, as compared to heavy platelets, but an equal number of mitochondria for both groups. These differences of platelet volume and structure between light and heavy platelets suggested that aging may be a determinant of platelet heterogeneity." @default.
- W2327484480 created "2016-06-24" @default.
- W2327484480 creator A5051775780 @default.
- W2327484480 creator A5071319027 @default.
- W2327484480 creator A5073881396 @default.
- W2327484480 date "1977-01-01" @default.
- W2327484480 modified "2023-10-16" @default.
- W2327484480 title "Heterogeneity of human whole blood platelet subpopulations. I. Relationship between buoyant density, cell volume, and ultrastructure" @default.
- W2327484480 cites W118160450 @default.
- W2327484480 cites W13788639 @default.
- W2327484480 cites W1505364422 @default.
- W2327484480 cites W154111426 @default.
- W2327484480 cites W155857247 @default.
- W2327484480 cites W1811074446 @default.
- W2327484480 cites W189812261 @default.
- W2327484480 cites W191818889 @default.
- W2327484480 cites W1983530319 @default.
- W2327484480 cites W1986039575 @default.
- W2327484480 cites W1986091223 @default.
- W2327484480 cites W1994400225 @default.
- W2327484480 cites W2006327668 @default.
- W2327484480 cites W2021855648 @default.
- W2327484480 cites W2022352581 @default.
- W2327484480 cites W2045245142 @default.
- W2327484480 cites W2061891312 @default.
- W2327484480 cites W2073047281 @default.
- W2327484480 cites W2075958491 @default.
- W2327484480 cites W2078328099 @default.
- W2327484480 cites W2084995423 @default.
- W2327484480 cites W2087992035 @default.
- W2327484480 cites W2088371504 @default.
- W2327484480 cites W2094946391 @default.
- W2327484480 cites W2141436795 @default.
- W2327484480 cites W2145471830 @default.
- W2327484480 cites W2147317334 @default.
- W2327484480 cites W2152700768 @default.
- W2327484480 cites W2155055244 @default.
- W2327484480 cites W2287074214 @default.
- W2327484480 cites W2317647309 @default.
- W2327484480 cites W2319133769 @default.
- W2327484480 cites W2322148932 @default.
- W2327484480 cites W2325596206 @default.
- W2327484480 cites W2332058631 @default.
- W2327484480 cites W2352322490 @default.
- W2327484480 cites W2401271977 @default.
- W2327484480 cites W2402101410 @default.
- W2327484480 cites W2408459082 @default.
- W2327484480 cites W2409578844 @default.
- W2327484480 cites W2409604495 @default.
- W2327484480 cites W2411094140 @default.
- W2327484480 cites W2419012382 @default.
- W2327484480 cites W2465232719 @default.
- W2327484480 cites W2465575287 @default.
- W2327484480 cites W2469664437 @default.
- W2327484480 cites W2471624727 @default.
- W2327484480 cites W35410649 @default.
- W2327484480 cites W187339646 @default.
- W2327484480 cites W2421344104 @default.
- W2327484480 doi "https://doi.org/10.1182/blood.v49.1.71.71" @default.
- W2327484480 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/830377" @default.
- W2327484480 hasPublicationYear "1977" @default.
- W2327484480 type Work @default.
- W2327484480 sameAs 2327484480 @default.
- W2327484480 citedByCount "277" @default.
- W2327484480 countsByYear W23274844802012 @default.
- W2327484480 countsByYear W23274844802013 @default.
- W2327484480 countsByYear W23274844802014 @default.
- W2327484480 countsByYear W23274844802015 @default.
- W2327484480 countsByYear W23274844802016 @default.
- W2327484480 countsByYear W23274844802017 @default.
- W2327484480 countsByYear W23274844802018 @default.
- W2327484480 countsByYear W23274844802019 @default.
- W2327484480 countsByYear W23274844802020 @default.
- W2327484480 countsByYear W23274844802021 @default.
- W2327484480 countsByYear W23274844802022 @default.
- W2327484480 countsByYear W23274844802023 @default.
- W2327484480 crossrefType "journal-article" @default.
- W2327484480 hasAuthorship W2327484480A5051775780 @default.
- W2327484480 hasAuthorship W2327484480A5071319027 @default.
- W2327484480 hasAuthorship W2327484480A5073881396 @default.
- W2327484480 hasBestOaLocation W23274844801 @default.
- W2327484480 hasConcept C105702510 @default.
- W2327484480 hasConcept C121332964 @default.
- W2327484480 hasConcept C126322002 @default.
- W2327484480 hasConcept C134018914 @default.
- W2327484480 hasConcept C150867306 @default.
- W2327484480 hasConcept C151730666 @default.
- W2327484480 hasConcept C185592680 @default.
- W2327484480 hasConcept C190481736 @default.
- W2327484480 hasConcept C20556612 @default.
- W2327484480 hasConcept C2776993930 @default.
- W2327484480 hasConcept C2992606362 @default.
- W2327484480 hasConcept C43617362 @default.
- W2327484480 hasConcept C49760210 @default.
- W2327484480 hasConcept C552990157 @default.
- W2327484480 hasConcept C55493867 @default.
- W2327484480 hasConcept C62520636 @default.
- W2327484480 hasConcept C71924100 @default.