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- W2327641916 endingPage "083" @default.
- W2327641916 startingPage "073" @default.
- W2327641916 abstract "Neuropathic pain (NP), a common form of human pain, often poorly responds to analgesic medications. In this review the authors discuss the pathophysiology and conventional treatment of neuropathic pain and provide evidenced-based statements on the efficacy of botulinum neurotoxins (BoNTs) in this form of pain. The level of efficacy for BoNT treatment in each category of NP is defined according to the published guidelines of the American Academy of Neurology. The data indicate that BoNT treatment (most of the literature is with onabotulinumtoxinA) is effective (level A evidence) in postherpetic neuralgia and trigeminal neuralgia. It is probably effective (level B) in posttraumatic neuralgia and painful diabetic neuropathy. The data on complex regional pain syndrome, carpal tunnel syndrome, occipital neuralgia, and phantom limb pain are preliminary and await conduction of randomized, blinded clinical trials. Much remains to be learned about the most-effective dosage and technique of injection, optimum dilutions, and differences among BoNTs in the treatment of neuropathic pain." @default.
- W2327641916 created "2016-06-24" @default.
- W2327641916 creator A5055888670 @default.
- W2327641916 creator A5060584519 @default.
- W2327641916 creator A5065331492 @default.
- W2327641916 date "2016-02-11" @default.
- W2327641916 modified "2023-10-08" @default.
- W2327641916 title "Botulinum Toxin Treatment of Neuropathic Pain" @default.
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- W2327641916 doi "https://doi.org/10.1055/s-0036-1571953" @default.
- W2327641916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26866499" @default.