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- W2327756089 abstract "To determine whether the lithium clearance (CLi) method offers a distinct advantage in the assessment of distal nephron function in the isolated perfused rat kidney (IPRK), estimates of distal Na+ reabsorption (dTNa+) based on the CLi (dTNA (Li)) were compared to those based on free water clearance (dTNa+(H2O)). In the steady state, dTNa+ (Li) was as high as 5-fold greater than (dTNa+(H2O)). The gap was even larger during the first hour of perfusion. These differences indicate that the Cu method is far superior and more accurate than the CH2O method, suggesting that it may be an adequate means for estimating dTNa+ in the IPRK. The CLi, observations also suggest that even in the absence of ADH a significant amount of solute-free water is reabsorbed by the collecting ducts of the IPRK." @default.
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- W2327756089 date "1991-01-01" @default.
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- W2327756089 title "Lithium and Free Water Clearances in the .Isolated Perfused Kidney" @default.
- W2327756089 doi "https://doi.org/10.4197/med.1-1.9" @default.
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