FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2327808439> ?p ?o ?g. }

• W2327808439 endingPage "157" @default.
• W2327808439 startingPage "152" @default.
• W2327808439 abstract "Objectives In this study, we identified the protein kinases that play the most distinct roles in the occurrence of acute pancreatitis (AP). Methods Gene expression profile data were downloaded from Gene Expression Omnibus database (GSE3644). The sample was from caerulein-induced AP mice. The intersection of the differentially expressed genes in AP mice taken from a protein kinase database was obtained for screening of the protein kinase encoded genes that were differentially expressed. Database for annotation, visualization, and integrated discovery was used for the functional enrichment analysis. Kinase inhibitors that regulated these kinases were retrieved from PubMed through text mining. Results Twenty-nine differentially expressed kinase encoded genes were identified through screening. The functional enrichment analysis demonstrated that the functions of these genes were primarily enriched in “mitogen-activated protein kinase signaling pathway,” followed by “extracellular regulated protein kinases pathway,” “neurotrophin signaling pathway,” “adherens junction,” and “gap junction.” SRC and epidermal growth factor receptor (EGFR) were related to extracellular regulated protein kinases pathway and also related to adherens junction as well as gap junction. On the basis of the regulated kinases, the kinase inhibitors reported in the literature were classified into multiple groups. Conclusions EGFR and SRC may be coexpressed in AP. The kinase inhibitors working together in SRC and EGFR may play better efficacy in the treatment of AP." @default.
• W2327808439 created "2016-06-24" @default.
• W2327808439 creator A5000598821 @default.
• W2327808439 creator A5034796819 @default.
• W2327808439 creator A5037599467 @default.
• W2327808439 creator A5050921331 @default.
• W2327808439 creator A5062047914 @default.
• W2327808439 creator A5065560361 @default.
• W2327808439 creator A5073995543 @default.
• W2327808439 creator A5082869088 @default.
• W2327808439 creator A5085340735 @default.
• W2327808439 date "2015-01-01" @default.
• W2327808439 modified "2023-10-18" @default.
• W2327808439 title "Role of Kinase Epidermal Growth Factor Receptor and SRC in the Caerulein-Induced Acute Pancreatitis in Mice" @default.
• W2327808439 cites W1518843892 @default.
• W2327808439 cites W1589311660 @default.
• W2327808439 cites W1970079141 @default.
• W2327808439 cites W1982659889 @default.
• W2327808439 cites W1982729445 @default.
• W2327808439 cites W1986136006 @default.
• W2327808439 cites W1988893353 @default.
• W2327808439 cites W1989064301 @default.
• W2327808439 cites W1992827477 @default.
• W2327808439 cites W2002096725 @default.
• W2327808439 cites W2003899579 @default.
• W2327808439 cites W2006945041 @default.
• W2327808439 cites W2015490567 @default.
• W2327808439 cites W2016830376 @default.
• W2327808439 cites W2021766527 @default.
• W2327808439 cites W2022847745 @default.
• W2327808439 cites W2026279585 @default.
• W2327808439 cites W2027546597 @default.
• W2327808439 cites W2036544212 @default.
• W2327808439 cites W2038484424 @default.
• W2327808439 cites W2046146724 @default.
• W2327808439 cites W2060509019 @default.
• W2327808439 cites W2064747278 @default.
• W2327808439 cites W2071311630 @default.
• W2327808439 cites W2076718022 @default.
• W2327808439 cites W2083045297 @default.
• W2327808439 cites W2083482432 @default.
• W2327808439 cites W2087311403 @default.
• W2327808439 cites W2093265249 @default.
• W2327808439 cites W2096468742 @default.
• W2327808439 cites W2100772783 @default.
• W2327808439 cites W2105361410 @default.
• W2327808439 cites W2112463023 @default.
• W2327808439 cites W2120395649 @default.
• W2327808439 cites W2123799914 @default.
• W2327808439 cites W2128307445 @default.
• W2327808439 cites W2128875373 @default.
• W2327808439 cites W2142752401 @default.
• W2327808439 cites W2146225376 @default.
• W2327808439 cites W2148429443 @default.
• W2327808439 cites W2156835140 @default.
• W2327808439 cites W2168158385 @default.
• W2327808439 cites W2171437346 @default.
• W2327808439 cites W2202622102 @default.
• W2327808439 doi "https://doi.org/10.1097/mpa.0000000000000219" @default.
• W2327808439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25222135" @default.
• W2327808439 hasPublicationYear "2015" @default.
• W2327808439 type Work @default.
• W2327808439 sameAs 2327808439 @default.
• W2327808439 citedByCount "4" @default.
• W2327808439 countsByYear W23278084392016 @default.
• W2327808439 countsByYear W23278084392017 @default.
• W2327808439 countsByYear W23278084392019 @default.
• W2327808439 crossrefType "journal-article" @default.
• W2327808439 hasAuthorship W2327808439A5000598821 @default.
• W2327808439 hasAuthorship W2327808439A5034796819 @default.
• W2327808439 hasAuthorship W2327808439A5037599467 @default.
• W2327808439 hasAuthorship W2327808439A5050921331 @default.
• W2327808439 hasAuthorship W2327808439A5062047914 @default.
• W2327808439 hasAuthorship W2327808439A5065560361 @default.
• W2327808439 hasAuthorship W2327808439A5073995543 @default.
• W2327808439 hasAuthorship W2327808439A5082869088 @default.
• W2327808439 hasAuthorship W2327808439A5085340735 @default.
• W2327808439 hasConcept C108636557 @default.
• W2327808439 hasConcept C124160383 @default.
• W2327808439 hasConcept C137361374 @default.
• W2327808439 hasConcept C1491633281 @default.
• W2327808439 hasConcept C149402561 @default.
• W2327808439 hasConcept C163035849 @default.
• W2327808439 hasConcept C184235292 @default.
• W2327808439 hasConcept C201508349 @default.
• W2327808439 hasConcept C502942594 @default.
• W2327808439 hasConcept C55493867 @default.
• W2327808439 hasConcept C62478195 @default.
• W2327808439 hasConcept C82495950 @default.
• W2327808439 hasConcept C86803240 @default.
• W2327808439 hasConcept C95444343 @default.
• W2327808439 hasConcept C97029542 @default.
• W2327808439 hasConcept C99405784 @default.
• W2327808439 hasConceptScore W2327808439C108636557 @default.
• W2327808439 hasConceptScore W2327808439C124160383 @default.
• W2327808439 hasConceptScore W2327808439C137361374 @default.
• W2327808439 hasConceptScore W2327808439C1491633281 @default.
• W2327808439 hasConceptScore W2327808439C149402561 @default.

• next