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- W2327841541 abstract "Objective To investigate the expression of CD95 and special marker for activation of peripheral blood lymphocytes in patients with hand foot and mouth disease (HFMD) and its significance. Methods Immunofluorescent two-color flow cytometry was used to study the expression of CD95 and HLA-DR on lymphocytes in 58 patients with HFMD and 34 normal controls. Results Expression of CD3~+ T cells was significantly lower in patients (63.82±7.74)% than that in controls (P 0.05). Conclusion The findings support that cellular immunodeficiency exists in patients and that lymphocytes were abnormally activated in the patients. The activation of peripheral blood T lymphocytes in patients mainly involves CD8~+ subset and it may play an important role in the immune response to antiviral infection.Key words: Hand, foot and mouth disease; T- lymphocytes; HLA-DR Antigens; Antigens,CD95" @default.
- W2327841541 created "2016-06-24" @default.
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- W2327841541 date "2010-02-01" @default.
- W2327841541 modified "2023-09-24" @default.
- W2327841541 title "The expression of CD95 and activated antigens in peripheral blood lymphocyte subsets in patients with hand foot and mouth disease (HFMD)" @default.
- W2327841541 doi "https://doi.org/10.3760/cma.j.issn.1003-9279.2010.01.012" @default.
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