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• W2327977772 abstract "Hexamethyldisiloxane (HMDO) has been developed to efficiently promote the metal-free direct coupling of an amino function of one cysteine-free peptide or protein and a C-terminal thioester of the second peptide in ionic liquids. The amide-coupling reaction proceeds smoothly under mild conditions to afford the corresponding products in good to excellent yields (63–94%). Peptide couplings were also achieved using in-situ-generated thioesters by the thioesterification of oxo esters." @default.
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• W2327977772 date "2013-07-05" @default.
• W2327977772 modified "2023-09-29" @default.
• W2327977772 title "HMDO-Promoted Peptide and Protein Synthesis in Ionic Liquids" @default.
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• W2327977772 doi "https://doi.org/10.1021/jo400797t" @default.
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