Matches in SemOpenAlex for { <https://semopenalex.org/work/W2328147592> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2328147592 endingPage "245" @default.
- W2328147592 startingPage "239" @default.
- W2328147592 abstract "Although many patients with severe emphysema have undergone lung-volume-reduction surgery, the benefits are uncertain. We conducted a randomized, controlled trial of the surgery in patients with emphysema. Patients with isolated bullae were excluded because such patients are known to improve after bullectomy.Potentially eligible patients were given intensive medical treatment and completed a smoking-cessation program and a six-week outpatient rehabilitation program before random assignment to surgery or continued medical treatment. After 15 patients had been randomized, the entry criteria were modified to exclude patients with a carbon monoxide gas-transfer value less than 30 percent of the predicted value or a shuttle-walking distance of less than 150 m, because of the deaths of 5 such patients (3 treated surgically and 2 treated medically).Of the 174 subjects who were initially assessed, 24 were randomly assigned to continued medical treatment and 24 to surgery. At base line in both groups, the median forced expiratory volume in one second (FEV1) was 0.75 liter, and the median shuttle-walking distance was 215 m. Five patients in the surgical group (21 percent) and three patients in the medical group (12 percent) died (P=0.43). After six months, the median FEV1 had increased by 70 ml in the surgical group and decreased by 80 ml in the medical group (P=0.02). The median shuttle-walking distance increased by 50 m in the surgical group and decreased by 20 m in the medical group (P=0.02). There were similar changes on a quality-of-life scale and similar changes at 12 months of follow-up. Five of the 19 surviving patients in the surgical group had no benefit from the treatment.In selected patients with severe emphysema, lung-volume-reduction surgery can improve FEV1, walking distance, and quality of life. Whether it reduces mortality is uncertain." @default.
- W2328147592 created "2016-06-24" @default.
- W2328147592 creator A5036400895 @default.
- W2328147592 creator A5037948017 @default.
- W2328147592 creator A5039981930 @default.
- W2328147592 creator A5044481124 @default.
- W2328147592 creator A5047693112 @default.
- W2328147592 creator A5058047435 @default.
- W2328147592 creator A5064147154 @default.
- W2328147592 creator A5079346001 @default.
- W2328147592 creator A5081219733 @default.
- W2328147592 creator A5088838023 @default.
- W2328147592 date "2000-07-27" @default.
- W2328147592 modified "2023-10-18" @default.
- W2328147592 title "Effect of Lung-Volume–Reduction Surgery in Patients with Severe Emphysema" @default.
- W2328147592 cites W1851493883 @default.
- W2328147592 cites W1977742001 @default.
- W2328147592 cites W1977944368 @default.
- W2328147592 cites W1993228703 @default.
- W2328147592 cites W2024645285 @default.
- W2328147592 cites W2026217381 @default.
- W2328147592 cites W2041532866 @default.
- W2328147592 cites W2072813786 @default.
- W2328147592 cites W2075911324 @default.
- W2328147592 cites W2078669720 @default.
- W2328147592 cites W2111999574 @default.
- W2328147592 cites W2118202495 @default.
- W2328147592 cites W2121561159 @default.
- W2328147592 cites W2135819121 @default.
- W2328147592 cites W2142927175 @default.
- W2328147592 cites W2153833649 @default.
- W2328147592 doi "https://doi.org/10.1056/nejm200007273430402" @default.
- W2328147592 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10911005" @default.
- W2328147592 hasPublicationYear "2000" @default.
- W2328147592 type Work @default.
- W2328147592 sameAs 2328147592 @default.
- W2328147592 citedByCount "371" @default.
- W2328147592 countsByYear W23281475922012 @default.
- W2328147592 countsByYear W23281475922013 @default.
- W2328147592 countsByYear W23281475922014 @default.
- W2328147592 countsByYear W23281475922015 @default.
- W2328147592 countsByYear W23281475922016 @default.
- W2328147592 countsByYear W23281475922017 @default.
- W2328147592 countsByYear W23281475922018 @default.
- W2328147592 countsByYear W23281475922019 @default.
- W2328147592 countsByYear W23281475922020 @default.
- W2328147592 countsByYear W23281475922021 @default.
- W2328147592 countsByYear W23281475922022 @default.
- W2328147592 countsByYear W23281475922023 @default.
- W2328147592 crossrefType "journal-article" @default.
- W2328147592 hasAuthorship W2328147592A5036400895 @default.
- W2328147592 hasAuthorship W2328147592A5037948017 @default.
- W2328147592 hasAuthorship W2328147592A5039981930 @default.
- W2328147592 hasAuthorship W2328147592A5044481124 @default.
- W2328147592 hasAuthorship W2328147592A5047693112 @default.
- W2328147592 hasAuthorship W2328147592A5058047435 @default.
- W2328147592 hasAuthorship W2328147592A5064147154 @default.
- W2328147592 hasAuthorship W2328147592A5079346001 @default.
- W2328147592 hasAuthorship W2328147592A5081219733 @default.
- W2328147592 hasAuthorship W2328147592A5088838023 @default.
- W2328147592 hasBestOaLocation W23281475921 @default.
- W2328147592 hasConcept C126322002 @default.
- W2328147592 hasConcept C141071460 @default.
- W2328147592 hasConcept C168563851 @default.
- W2328147592 hasConcept C27101514 @default.
- W2328147592 hasConcept C2775982285 @default.
- W2328147592 hasConcept C2777714996 @default.
- W2328147592 hasConcept C71924100 @default.
- W2328147592 hasConceptScore W2328147592C126322002 @default.
- W2328147592 hasConceptScore W2328147592C141071460 @default.
- W2328147592 hasConceptScore W2328147592C168563851 @default.
- W2328147592 hasConceptScore W2328147592C27101514 @default.
- W2328147592 hasConceptScore W2328147592C2775982285 @default.
- W2328147592 hasConceptScore W2328147592C2777714996 @default.
- W2328147592 hasConceptScore W2328147592C71924100 @default.
- W2328147592 hasIssue "4" @default.
- W2328147592 hasLocation W23281475921 @default.
- W2328147592 hasLocation W23281475922 @default.
- W2328147592 hasOpenAccess W2328147592 @default.
- W2328147592 hasPrimaryLocation W23281475921 @default.
- W2328147592 hasRelatedWork W1930520419 @default.
- W2328147592 hasRelatedWork W2011474955 @default.
- W2328147592 hasRelatedWork W2021073609 @default.
- W2328147592 hasRelatedWork W2063351187 @default.
- W2328147592 hasRelatedWork W2140798738 @default.
- W2328147592 hasRelatedWork W2276860053 @default.
- W2328147592 hasRelatedWork W2377217162 @default.
- W2328147592 hasRelatedWork W2402421840 @default.
- W2328147592 hasRelatedWork W2418097383 @default.
- W2328147592 hasRelatedWork W2493421712 @default.
- W2328147592 hasVolume "343" @default.
- W2328147592 isParatext "false" @default.
- W2328147592 isRetracted "false" @default.
- W2328147592 magId "2328147592" @default.
- W2328147592 workType "article" @default.