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- W2328163907 abstract "Background: The aim of our study was to elucidate the impact on incidence and prognosis of the new 2012 universial definition of myocardial infarction Type 2. Methods: In a prospective international multicenter study, we enrolled 1778 consecutive patients presenting with suspected acute myocardial infarction (AMI) to the emergency department. The final diagnosis was adjudicated by 2 independent cardiologists twice: once according to the 2007 universial definition in which the presence of coronary artery disease was a requirement for AMI Type II, and once according to the more liberal 2012 universial definition no longer requiring coronary artery disease. Long-term follow-up was performed in all patients for a mean of 54±28 months. Results: The application of the definition of AMI Type 2 according to the 2012 universial definition resulted in an increase in the incidence of AMI Type 2 from 2.5% to 6.4% (114 vs 45 patients), a relative increase of 153%. Cumulative 41–month mortality rates were 4.7% in patients without AMI, 4.8% in patients reclassified according the new defined Type 2 AMI using the 2012 guidelines, and 8.3% in patients with a Type 2 AMI according to the 2007 universial definition. Conclusions: These data from a large prospective cohort of consecutive patients presenting with acute chest pain indicate that the changes made in the 2012 universial definition of Type II AMI more than double the incidence of this diagnosis. These reclassified Type II AMI patients have a long-term mortality that is similar to patients without AMI and much lower as compared to Type II AMI patients according to the 2007 universial definition. Our data will be helpful in the ongoing discussion about whether it is really appropriate to label these events as AMI." @default.
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- W2328163907 date "2013-08-02" @default.
- W2328163907 modified "2023-09-26" @default.
- W2328163907 title "New 2012 universial definition of myocardial infarction type 2" @default.
- W2328163907 doi "https://doi.org/10.1093/eurheartj/eht311.5905" @default.
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