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- W2328178721 abstract "Physiological changes of a concentration of the erythrocyte 2, 3-diphosphoglycerate (2, 3-DPG) were investigated in the elderly subjects with reference to an effect of aging. They consisted of 59 healthy subjects over 60 years old, 32 males and 27 females. Measurement of 2, 3-DPG was carried out using the 2, 3-DPG kit (Boehringer. Mannheim Inc.). The results obtained were as follows : 1) Mean concentrations of the erythrocyte 2, 3-DPG were 15.8±2.4, 16.0±1.5 and 15.9±1.3 μmol/g Hb for the males, 18.0±2.2, 17.2±2.3 and 17.2±2.2 μmol/g Hb for the females in the age groups of 60 to 69, 70 to 79 and 80 to 89 years old, respectively. All of these values were significantly higher than that of the younger group of 20 to 39 years old, while mean Hb values were significantly lower in all groups of the elderly than in the younger.2) There was a highly significant negative correlation between concentrations of the erythrocyte 2, 3-DPG and Hb values in all subjects including the elderly and the younger. Although such a correlation was similarly observed in both males and females, an increment of 2, 3-DPG responding to a given decrease of Hb value was of relatively slight degree in the males comparing with the females.From these observations it is suggested that a higher concentration of the erythrocyte 2, 3-DPG in the elderly than in the younger may result from an enhancement of production of the erythrocyte 2, 3-DPG in response to lowering of Hb level in the elderly population." @default.
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- W2328178721 date "1980-01-01" @default.
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- W2328178721 title "STUDY ON ERYTHROCYTE 2, 3-DIPHOSPHOGLYCERATE IN ELDERLY SUBJECTS" @default.
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- W2328178721 doi "https://doi.org/10.2974/kmj1951.30.4_221" @default.
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