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• W2328205604 abstract "Women with a history of gestational diabetes mellitus (GDM) are at increased risk of developing type 2 diabetes mellitus in the future. Risk factors common to both GDM and type 2 diabetes include overweight and obesity. The risk of GDM increases substantially with increasing prepregnancy body mass index (BMI), but the percentage of GDM attributable to overweight and obesity is not known. It is possible that a significant percentage of GDM cases potentially attributable to overweight and obesity could be avoided by preventing these conditions using weight management strategies. The objectives of this population-based study were to calculate the percentage of GDM attributable to overweight and obesity for different BMI categories, to estimate the contribution of elevations in BMI to the prevalence of GDM, and to examine the possible role of weight management on GDM prevalence. Data were obtained from the Pregnancy Risk Assessment Monitoring System, a population-based surveillance system. The study population included 23,904 women who were surveyed between 2004 and 2006 in 7 states that had implemented the 2003 revised US birth certificate (including data on GDM separate from pre-existing diabetes). Multiple logistic regression analysis was used to estimate both the proportion of GDM attributable to overweight and obesity (population-attributable fraction) and the association between BMI and GDM. The GDM prevalence was calculated for the following BMI categories: underweight (13–18.4 kg/m2); normal weight (18.5–24.9 kg/m2); overweight (25–29.9 kg/m2); obese (30–34.9 kg/m2); and extremely obese (35–64.9 kg/m2). The data showed increased risk of GDM with increasing BMI. The GDM prevalence according to BMI category was as follows: underweight, 0.7%; normal weight, 2.3%; overweight, 4.8%; obese, 5.5%; and extremely obese, 11.5%. The adjusted percentages of GDM attributable to overweight, obesity, and extreme obesity were 15.4% (95% confidence interval [CI], 8.6–22.2), 9.7% (95% CI, 5.2–14.3), and 21.1% (95% CI, 15.2–26.9), respectively. The overall population-attributable fraction due to overweight and obesity was 46.2% (95% CI, 36.1–56.3). These findings suggest that almost half of GDM cases could be prevented if all overweight and obese women with BMI ≥ 25 kg/m2 had a GDM risk equal to that of normal-weight women. Because lifestyle interventions that reduce BMI have the potential to lower GDM risk, public health efforts should be intensified to improve eating habits in women of reproductive age." @default.
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• W2328205604 date "2010-10-01" @default.
• W2328205604 modified "2023-10-18" @default.
• W2328205604 title "Percentage of Gestational Diabetes Mellitus Attributable to Overweight and Obesity" @default.
• W2328205604 doi "https://doi.org/10.1097/ogx.0b013e3182021f5a" @default.
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