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- W2328366999 endingPage "21" @default.
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- W2328366999 abstract "Review of randomized controlled trials of nutritional supplementation in people living with HIV Alicia Sneij, Adriana Campa, Marianna K Baum Stempel College of Public Health and Social Work, Florida International University, Modesto Maidique Campus, Miami, FL, USA Background: Nutritional deficiencies are widespread in people living with HIV (PLWH), prior to the antiretroviral treatment (ART). Nutrient deficiencies and other nutrition-related conditions, however, have been identified in patients receiving ART. Trials of nutritional supplementation have been conducted to alleviate these nutritional conditions and improve or reverse nutrition-related outcomes. This review aims to evaluate the benefits of supplementation, its unintended adverse effects, and the difference in approach and focus, research design, formulations, and outcomes between those randomized clinical trials (RCTs) conducted before and after the initiation of ART. Methods: An evidence-based systematic review of the literature was conducted using electronic databases and the resources of the Florida International University Research Library. Forty-two RCTs were selected for review, and their design and outcomes were compared and contrasted conceptually and in the form of tables. Results: Most of the RCTs (n=31) were conducted before the advent of ART, and their aims were delaying disease progression, reversing malnutrition, and improving pregnancy outcomes in women and infants infected with HIV. The RCTs conducted with coadministration of ART were fewer (n=11), with relative smaller sample size, of shorter duration, and mainly focused on preventing or ameliorating the nutrition-related conditions generated by the chronic infection, its treatment, and the aging of PLWH. Conclusion: As ART is becoming more accessible worldwide, and people are living longer with the disease, more longitudinal trials of nutritional interventions with larger sample sizes are needed to study the nutritional consequences and potential treatments for PLWH. Keywords: HIV, antiretroviral therapy, micronutrients, probiotics, AIDS, randomization, clinical trial" @default.
- W2328366999 created "2016-06-24" @default.
- W2328366999 creator A5061697132 @default.
- W2328366999 creator A5080579925 @default.
- W2328366999 creator A5090142867 @default.
- W2328366999 date "2016-04-01" @default.
- W2328366999 modified "2023-10-18" @default.
- W2328366999 title "Review of randomized controlled trials of nutritional supplementation in people living with HIV" @default.
- W2328366999 cites W1408540431 @default.
- W2328366999 cites W1588279707 @default.
- W2328366999 cites W1772245087 @default.
- W2328366999 cites W1860213393 @default.
- W2328366999 cites W1958209244 @default.
- W2328366999 cites W1959323956 @default.
- W2328366999 cites W1960774341 @default.
- W2328366999 cites W1964895167 @default.
- W2328366999 cites W1968233962 @default.
- W2328366999 cites W1968465136 @default.
- W2328366999 cites W1972055433 @default.
- W2328366999 cites W1973855900 @default.
- W2328366999 cites W1974075607 @default.
- W2328366999 cites W1974293584 @default.
- W2328366999 cites W1976189867 @default.
- W2328366999 cites W1988398351 @default.
- W2328366999 cites W2000807256 @default.
- W2328366999 cites W2002644253 @default.
- W2328366999 cites W2003362216 @default.
- W2328366999 cites W2005046839 @default.
- W2328366999 cites W2006269988 @default.
- W2328366999 cites W2009494928 @default.
- W2328366999 cites W2010212133 @default.
- W2328366999 cites W2010284009 @default.
- W2328366999 cites W2011758289 @default.
- W2328366999 cites W2016488838 @default.
- W2328366999 cites W2017614850 @default.
- W2328366999 cites W2019638881 @default.
- W2328366999 cites W2021897148 @default.
- W2328366999 cites W2021973864 @default.
- W2328366999 cites W2024965238 @default.
- W2328366999 cites W2027417729 @default.
- W2328366999 cites W2027606261 @default.
- W2328366999 cites W2029625589 @default.
- W2328366999 cites W2030218289 @default.
- W2328366999 cites W2030944051 @default.
- W2328366999 cites W2031004350 @default.
- W2328366999 cites W2034204613 @default.
- W2328366999 cites W2035458885 @default.
- W2328366999 cites W2036505093 @default.
- W2328366999 cites W2041841997 @default.
- W2328366999 cites W2042430050 @default.
- W2328366999 cites W2048497884 @default.
- W2328366999 cites W2049099387 @default.
- W2328366999 cites W2051191950 @default.
- W2328366999 cites W2057117085 @default.
- W2328366999 cites W2059662993 @default.
- W2328366999 cites W2059783243 @default.
- W2328366999 cites W2059936972 @default.
- W2328366999 cites W2062139143 @default.
- W2328366999 cites W2062437104 @default.
- W2328366999 cites W2069293936 @default.
- W2328366999 cites W2072778332 @default.
- W2328366999 cites W2073336153 @default.
- W2328366999 cites W2080810160 @default.
- W2328366999 cites W2081469615 @default.
- W2328366999 cites W2082407676 @default.
- W2328366999 cites W2082697314 @default.
- W2328366999 cites W2083887997 @default.
- W2328366999 cites W2088968901 @default.
- W2328366999 cites W2089780776 @default.
- W2328366999 cites W2095250461 @default.
- W2328366999 cites W2096946443 @default.
- W2328366999 cites W2099002304 @default.
- W2328366999 cites W2104289572 @default.
- W2328366999 cites W2106093671 @default.
- W2328366999 cites W2107606668 @default.
- W2328366999 cites W2109000845 @default.
- W2328366999 cites W2112972873 @default.
- W2328366999 cites W2114405620 @default.
- W2328366999 cites W2115075919 @default.
- W2328366999 cites W2118805834 @default.
- W2328366999 cites W2118888586 @default.
- W2328366999 cites W2119271887 @default.
- W2328366999 cites W2119976710 @default.
- W2328366999 cites W2120426044 @default.
- W2328366999 cites W2121303369 @default.
- W2328366999 cites W2121753052 @default.
- W2328366999 cites W2122483069 @default.
- W2328366999 cites W2124172118 @default.
- W2328366999 cites W2124892937 @default.
- W2328366999 cites W2125487560 @default.
- W2328366999 cites W2125653245 @default.
- W2328366999 cites W2125870297 @default.
- W2328366999 cites W2128109602 @default.
- W2328366999 cites W2128698112 @default.
- W2328366999 cites W2129755986 @default.
- W2328366999 cites W2130255026 @default.
- W2328366999 cites W2130603879 @default.
- W2328366999 cites W2131467623 @default.