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- W2328442314 abstract "Context: Bone fragility and low bone mass have been reported in small case series of patients with Pompe disease with severely reduced muscle strength or immobilization. Objective: Our objective was to determine the prevalence of morphometric vertebral fractures and to evaluate bone mass in adults with late-onset Pompe disease. Design: We conducted a multicenter cross-sectional observational study from August 2012 to December 2013. Study Setting: All subjects were outpatients referred to University Referral Centers. Patients: Patients included 22 late-onset Pompe disease patients with progressive proximal myopathy and minimal respiratory involvement without other diseases affecting bone mass. Main Outcome Measure: The prevalence of morphometric vertebral fractures was systematically assessed by semiquantitative analysis of lateral spine x-rays (T4–L5). Results: A high prevalence of morphometric vertebral fractures was found. At least 1 vertebral fracture was present in 17 of 22 patients (77%). All vertebr..." @default.
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- W2328442314 date "2015-01-01" @default.
- W2328442314 modified "2023-09-24" @default.
- W2328442314 title "Prevalence of Asymptomatic Vertebral Fractures in Late-Onset Pompe Disease" @default.
- W2328442314 doi "https://doi.org/10.3233/jnd-159013" @default.
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